Findings

What do systematic reviews say?

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

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No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Low‐level laser therapy vs simple dressing

Primary outcome: prevention of ulcer · ulceration and other skin changes caused by nerve damage in leprosy

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low‐level laser therapy vs simple dressing

Ulcer healing · ulceration and other skin changes caused by nerve damage in leprosy

2 findings from 1 review

Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 23 participants
Very low
Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 23 participants
Very low

Low‐level laser therapy vs simple dressing

Adverse events associated with treatment · ulceration and other skin changes caused by nerve damage in leprosy

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low‐level laser therapy vs simple dressing

Secondary outcome: quality of life · ulceration and other skin changes caused by nerve damage in leprosy

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low‐level laser therapy vs simple dressing

Secondary outcome: acceptability of treatment · ulceration and other skin changes caused by nerve damage in leprosy

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low‐level laser therapy vs simple dressing

Costs · ulceration and other skin changes caused by nerve damage in leprosy

1 finding from 1 review

Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 23 participants
Very low

Low frequency ultrasound vs no ultrasound

Ulcers completely healed · venous leg ulcers

It is very uncertain whether low frequency ultrasound changes proportion of ulcers completely healed at 8 to 12 weeks compared with no ultrasound (very low certainty).

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
RR 3.91 [0.47, 32.85]
2 studies · 61 participants
Very low

Low frequency ultrasound vs no ultrasound

Adverse events · venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low frequency ultrasound vs no ultrasound

Health‐related quality of life · venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low frequency ultrasound vs no ultrasound

Costs · venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Effect of low‐dose alcohol vs placebo

Systolic blood pressure · adult participants

1 finding from 1 review

Effect of alcohol on blood pressure 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 28 participants
Low

Effect of low‐dose alcohol vs placebo

Diastolic blood pressure · adult participants

1 finding from 1 review

Effect of alcohol on blood pressure 2020 · Cochrane Headline outcomes only
no estimate extracted
28 participants
Low

Effect of low‐dose alcohol vs placebo

Heart rate · adult participants

1 finding from 1 review

Effect of alcohol on blood pressure 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 28 participants
Moderate

Low GDP (all buffer types) vs standard glucose dialysate

Residual renal function (GFR; · PD patients

1 finding from 1 review

Biocompatible dialysis fluids for peritoneal dialysis 2018 · Cochrane Headline outcomes only
no estimate extracted
15 studies · 835 participants
High

Low GDP (all buffer types) vs standard glucose dialysate

Urine volume ( · PD patients

1 finding from 1 review

Biocompatible dialysis fluids for peritoneal dialysis 2018 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 791 participants
High

Low GDP (all buffer types) vs standard glucose dialysate

Peritoneal ultrafiltration ‐ 4 hours (mL/4 hours) ( · PD patients

1 finding from 1 review

Biocompatible dialysis fluids for peritoneal dialysis 2018 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 414 participants
Low

Low GDP (all buffer types) vs standard glucose dialysate

Peritoneal solute transport rate (4‐hour dialysis:plasma creatinine) ( · PD patients

1 finding from 1 review

Biocompatible dialysis fluids for peritoneal dialysis 2018 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 746 participants
Low

Low GDP (all buffer types) vs standard glucose dialysate

Peritonitis · PD patients

Low GDP (all buffer types) showed no clear difference in peritonitis rate (episodes/total patient‐months) (up to 24 months) compared with standard glucose dialysate (low certainty).

1 finding from 1 review

Biocompatible dialysis fluids for peritoneal dialysis 2018 · Cochrane Headline outcomes only
RR 1.18 [0.84, 1.64]
10 studies · 18184 participants
Low

Low GDP (all buffer types) vs standard glucose dialysate

Technique failure (death‐censored) ( · PD patients

Low GDP (all buffer types) showed no clear difference in technique failure (death‐censored) ( compared with standard glucose dialysate (low certainty).

1 finding from 1 review

Biocompatible dialysis fluids for peritoneal dialysis 2018 · Cochrane Headline outcomes only
RR 1.1 [0.75, 1.63]
15 studies · 1275 participants
Low

Low GDP (all buffer types) vs standard glucose dialysate

Death (all causes) ( · PD patients

Low GDP (all buffer types) showed no clear difference in death (all causes) ( compared with standard glucose dialysate (low certainty).

1 finding from 1 review

Biocompatible dialysis fluids for peritoneal dialysis 2018 · Cochrane Headline outcomes only
RR 0.73 [0.47, 1.14]
1229 participants
Low