Findings

What do systematic reviews say?

1,057 questions · 1,077 findings · 32 reviews · Skin

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No studies found 395 · 36.7%GRADE not reported 89 · 8.3%Very low 172 · 16%Low 177 · 16.4%Moderate 191 · 17.7%High 53 · 4.9%

Paromomycin ointment vs vehicle

Time to complete healing · patients with Old World cutaneous leishmaniasis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for Old World cutaneous leishmaniasis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotic prophylaxis vs no treatment/placebo

Recurrence of cellulitis · People with recurrent erysipelas or cellulitis

Antibiotic prophylaxis probably leads to lower recurrence of cellulitis compared with no treatment/placebo (moderate certainty).

1 finding from 1 review

Interventions for the prevention of recurrent erysipelas and cellulitis 2017 · Cochrane Headline outcomes only
RR 0.31 [0.13, 0.72]
5 studies · 513 participants
Moderate

Antibiotic prophylaxis vs no treatment/placebo

Incidence rate of cellulitis · People with recurrent erysipelas or cellulitis

Antibiotic prophylaxis probably leads to lower incidence rate of cellulitis compared with no treatment/placebo (moderate certainty).

1 finding from 1 review

Interventions for the prevention of recurrent erysipelas and cellulitis 2017 · Cochrane Headline outcomes only
RR 0.44 [0.22, 0.89]
4 studies · 473 participants
Moderate

Antibiotic prophylaxis vs no treatment/placebo

Time to next episode of cellulitis · People with recurrent erysipelas or cellulitis

Antibiotic prophylaxis probably leads to lower time to next episode of cellulitis compared with no treatment/placebo (moderate certainty).

1 finding from 1 review

Interventions for the prevention of recurrent erysipelas and cellulitis 2017 · Cochrane Headline outcomes only
HR 0.51 [0.34, 0.78]
3 studies · 437 participants
Moderate

Antibiotic prophylaxis vs no treatment/placebo

Hospital admissions · People with recurrent erysipelas or cellulitis

Antibiotic prophylaxis showed no clear difference in hospitalisation compared with no treatment/placebo (low certainty).

1 finding from 1 review

Interventions for the prevention of recurrent erysipelas and cellulitis 2017 · Cochrane Headline outcomes only
RR 0.77 [0.37, 1.57]
3 studies · 429 participants
Low

Antibiotic prophylaxis vs no treatment/placebo

Adverse reactions to treatment Proportion of participants with adverse reactions to treatment · People with recurrent erysipelas or cellulitis

Antibiotic prophylaxis showed no clear difference in any adverse reactions compared with no treatment/placebo (low certainty).

1 finding from 1 review

Interventions for the prevention of recurrent erysipelas and cellulitis 2017 · Cochrane Headline outcomes only
RR 0.87 [0.58, 1.3]
4 studies · 469 participants
Low

Antibiotic prophylaxis vs no treatment/placebo

Quality of life · People with recurrent erysipelas or cellulitis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the prevention of recurrent erysipelas and cellulitis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Minoxidil vs placebo

Proportion of participants with self‐rated clinically significant hair regrowth · women with FPHL

Minoxidil probably leads to higher the proportion of participants with self‐rated clinically… compared with placebo (moderate certainty).

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
RR 1.93 [1.51, 2.47]
6 studies · 1148 participants
Moderate

Minoxidil 2% vs minoxidil 5%

Change in quality of life · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 209 participants
Low

Minoxidil 2% vs minoxidil 5%

Adverse events · women with FPHL

Minoxidil 2% showed no clear difference in adverse events compared with minoxidil 5% (low certainty).

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
RR 1.02 [0.91, 1.2]
4 studies · 1006 participants
Low

Minoxidil 2% vs minoxidil 5%

Proportion of participants with investigator‐rated clinically significant hair regrowth · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 586 participants
Moderate

Minoxidil 2% vs minoxidil 5%

Change from baseline to study conclusion in total hair count · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 631 participants
Low

Minoxidil 2% vs minoxidil 5%

Degree of hair shedding from baseline to the end of the study · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Minoxidil 2% vs minoxidil 5%

Cosmetic appearance of the hair or participant satisfaction · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 322 participants
Moderate

Minoxidil 2% vs minoxidil 5%

Change in quality (or pattern) of hair regrowth (e.g. thickness) · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 322 participants
Moderate

Finasteride vs placebo

Proportion of participants with self‐rated clinically significant hair regrowth · women with FPHL

Finasteride showed no clear difference in the proportion of participants with self‐rated clinically… compared with placebo (low certainty).

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
RR 0.95 [0.66, 1.37]
1 study · 137 participants
Low

Finasteride vs placebo

Change in quality of life ‐ not measured · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Finasteride vs placebo

Adverse events · women with FPHL

Finasteride showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
RR 1.03 [0.45, 2.34]
1 study · 137 participants
Low

Minoxidil vs placebo

Change in quality of life · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 260 participants
Low

Finasteride vs placebo

Proportion of participants with investigator‐rated clinically significant hair regrowth · women with FPHL

Finasteride showed no clear difference in proportion of participants with investigator‐rated clinically… compared with placebo (low certainty).

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
RR 0.77 [0.31, 1.9]
1 study · 137 participants
Low