Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

970 questions · 979 findings · 135 reviews

No studies found 182 · 18.6%GRADE not reported 84 · 8.6%Very low 165 · 16.9%Low 311 · 31.8%Moderate 163 · 16.6%High 74 · 7.6%

Tacrolimus vs mycophenolate mofetil to maintain remission

Primary outcome: partial clinical response · idiopathic steroid‐resistant nephrotic syndrome in children

Tacrolimus showed no clear difference in number with partial response at one year compared with mycophenolate mofetil to maintain remission (low certainty).

1 finding from 1 review

Tacrolimus vs mycophenolate mofetil to maintain remission

Number with steroid resistance by one year · idiopathic steroid‐resistant nephrotic syndrome in children

Tacrolimus showed no clear difference in number with steroid resistance by one year compared with mycophenolate mofetil to maintain remission (low certainty).

1 finding from 1 review

Physical breastfeeding support interventions (electric or manual breast pump) vs usual care (no pump)

Non‐initiation of breastfeeding · women with a pre‐pregnancy BMI > 29 kg/m², who were intending to breastfeed, had no history of breast surgery, who were at least 19 years…

The review found no eligible studies for this question.

1 finding from 1 review

Physical breastfeeding support interventions (electric or manual breast pump) vs usual care (no pump)

Exclusive breastfeeding at 4‐6 weeks · women with a pre‐pregnancy BMI > 29 kg/m², who were intending to breastfeed, had no history of breast surgery, who were at least 19 years…

It is very uncertain whether physical breastfeeding support interventions (electric or manual… changes exclusive breastfeeding at 4‐6 weeks compared with usual care (no pump) (very low certainty).

1 finding from 1 review

Physical breastfeeding support interventions (electric or manual breast pump) vs usual care (no pump)

Breastfeeding · women with a pre‐pregnancy BMI > 29 kg/m², who were intending to breastfeed, had no history of breast surgery, who were at least 19 years…

It is very uncertain whether physical breastfeeding support interventions (electric or manual… changes any breastfeeding at 4‐6 weeks compared with usual care (no pump) (very low certainty).

2 findings from 1 review

Physical breastfeeding support interventions (electric or manual breast pump) vs usual care (no pump)

Exclusive breastfeeding at 6 months · women with a pre‐pregnancy BMI > 29 kg/m², who were intending to breastfeed, had no history of breast surgery, who were at least 19 years…

The review found no eligible studies for this question.

1 finding from 1 review

Planned elective birth (induction or caesarean) vs expectant management

Serious maternal morbidity or death · pregnant women with gestational diabetes, between 38 ‐ 39 gestational weeks, without other maternal or fetal conditions.

It is very uncertain whether planned elective birth (induction or caesarean) changes maternal mortality or serious maternal morbidity compared with expectant management (very low certainty).

1 finding from 1 review

Planned elective birth (induction or caesarean) vs expectant management

Caesarean section · pregnant women with gestational diabetes, between 38 ‐ 39 gestational weeks, without other maternal or fetal conditions.

It is very uncertain whether planned elective birth (induction or caesarean) changes caesarean section compared with expectant management (very low certainty).

1 finding from 1 review

Planned elective birth (induction or caesarean) vs expectant management

Instrumental vaginal birth · pregnant women with gestational diabetes, between 38 ‐ 39 gestational weeks, without other maternal or fetal conditions.

It is very uncertain whether planned elective birth (induction or caesarean) changes instrumental vaginal birth compared with expectant management (very low certainty).

1 finding from 1 review