Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Population

Intervention or exposure

Comparison

Outcome

Any field or review title

Field or topic

Source

Review versions

1,518 questions in 135 reviews · Infectious Diseases

current versions

No studies 135 · 8.9%Ungraded 150 · 9.9%Very low 350 · 23.1%Low 420 · 27.7%Moderate 321 · 21.1%High 142 · 9.4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Question	Effect	Evidence	Status / GRADE
Cotrimoxazole vs furazolidone Relapse ‐ not reported · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	no estimate extracted	NR	No studies
Cotrimoxazole vs furazolidone Serious adverse events · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	RR 0 [0, 0]	0 studies · 0 participants	Ungraded
Cotrimoxazole vs furazolidone Other adverse events ‐ not reported · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	no estimate extracted	NR	No studies
Oral gentamicin vs nalidixic acid Diarrhoea at · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	RR 1.71 [0.98, 2.97]	1 study · 79 participants	Very low
Oral gentamicin vs nalidixic acid Relapse ‐ not reported · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	no estimate extracted	NR	No studies
Oral gentamicin vs nalidixic acid Serious adverse events ‐ not reported · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	no estimate extracted	NR	No studies
Antibiotic vs no drug or placebo Relapse ‐ not reported · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	no estimate extracted	NR	No studies
Oral gentamicin vs nalidixic acid Other adverse events ‐ not reported · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	no estimate extracted	NR	No studies
Sulphonamides vs tetracycline Diarrhoea at · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	RR 7.68 [0.46, 128.12]	1 study · 60 participants	Very low
Sulphonamides vs tetracycline Relapse ‐ not reported · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	no estimate extracted	NR	No studies
Sulphonamides vs tetracycline Serious adverse events ‐ not reported · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	no estimate extracted	NR	No studies
Sulphonamides vs tetracycline Other adverse events ‐ not reported · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	no estimate extracted	NR	No studies
Antibiotic vs no drug or placebo Serious adverse events ‐ not reported · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	no estimate extracted	NR	No studies
Antibiotic vs no drug or placebo Other adverse events clinical criteria · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	RR 1.43 [0.06, 34.13]	1 study · 94 participants	Very low
Fluoroquinolones vs beta‐lactams Diarrhoea on · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	RR 1.03 [0.45, 2.37]	6 studies · 686 participants	Very low
Fluoroquinolones vs beta‐lactams Relapse ‐ All trials clinical criteria · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	RR 0.91 [0.11, 7.55]	3 studies · 357 participants	Very low
Fluoroquinolones vs beta‐lactams Serious adverse events clinical criteria · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	RR 10.9 [0.61, 194.82]	1 study · 221 participants	Very low
Fluoroquinolones vs beta‐lactams Adverse events leading to discontinuation of treatment · patients with Shigella dysentery Antibiotic therapy for Shigella dysentery (2010) · Cochrane	RR 1.02 [0.27, 3.89]	1 study · 127 participants	Very low