Findings

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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Chlorhexidine vs boric acid

Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them

It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with boric acid (very low certainty).

2 findings from 1 review

Glass ionomer-based sealant vs No sealant (control/no treatment)

Retention of sealant (complete or partial retention) · Children with caries-free primary first molars (with or without caries on other teeth), aged 1-5 years (paediatric clinic/dental school,…
1 finding from 1 review
  • Sealants for preventing dental caries in primary teeth 2022 · Cochrane All outcomes
    6-30 months
    Chadwick 2005: one or more sealants fully/partially retained in 69 (31.2%) children at 12-30 months; Joshi 2019: at 12 months 75 (43.6%) teeth completely retained, 58 (33.7%) partially retained, 39 (22.7%) completely…
    2 studies
    GRADE not reported

Antibiotic prophylaxis before dental procedure vs placebo or no prophylaxis

Mortality or serious adverse events requiring hospital admission · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure

The review found no eligible studies for this question.

1 finding from 1 review

Single-visit root canal treatment vs Multiple-visit root canal treatment (two or more visits)

Pain at two weeks (postobturation) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption

Single-visit root canal treatment showed no clear difference in pain at two weeks (postobturation) compared with multiple-visit root canal treatment (two or more visits); GRADE not reported.

1 finding from 1 review

Autopolymerised sealant vs Light polymerised sealant

Retention of sealant (complete or partial retention) · Children with sound primary molars, aged 2-4 years (municipal dental clinics or hospital paediatric clinics, Denmark)

It is very uncertain whether autopolymerised sealant changes retention of sealant (complete or partial retention) compared with light polymerised sealant (very low certainty).

1 finding from 1 review

Fluoride-releasing resin-based sealant vs No sealant (control/no treatment)

Retention of sealant (complete or partial retention) · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department, dental hospital, France)
1 finding from 1 review
  • Sealants for preventing dental caries in primary teeth 2022 · Cochrane All outcomes
    12-24 months
    At 12 months, sealants on 96 (70.1%) surfaces completely retained, 25 (18.3%) partially retained, 16 (11.6%) completely lost; at 24 months, 58 (45.3%) completely retained, 29 (22.7%) partially retained, 41 (32%)…
    1 study
    GRADE not reported

Referral letter based on the common-sense model (CSM) of self-regulation vs Standard referral letter

Proportion of children with treated/untreated caries (receipt of dental care) · School children, primary schools in the USA

It is very uncertain whether referral letter based on the common-sense model (CSM) of… changes proportion of children with treated/untreated caries (receipt of… compared with standard referral letter (very low certainty).

1 finding from 1 review

Criteria-based screening with specific (personalised) referral letter vs Criteria-based screening with non-specific referral letter

Dental attendance at orthodontist · School children, secondary school in the UK (aged 11 to 13 years)

It is very uncertain whether criteria-based screening with specific (personalised) referral letter changes dental attendance at orthodontist compared with criteria-based screening with non-specific referral letter (very low certainty).

1 finding from 1 review

Recombinant bovine fibroblast growth factor gel vs control

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

Recombinant bovine fibroblast growth factor gel led to lower presence of dry socket compared with control; GRADE not reported.

1 finding from 1 review