Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

611 questions · 621 findings · 112 reviews

No studies found 53 · 8.5%GRADE not reported 70 · 11.3%Very low 91 · 14.7%Low 216 · 34.8%Moderate 152 · 24.5%High 39 · 6.3%

Inhaled steroids vs systemic steroids

Death or bronchopulmonary dysplasia at 36 weeks PMA · Neonates with developing BPD

Inhaled steroids showed no clear difference in death or BPD at 36 weeks' postmenstrual age compared with systemic steroids (moderate certainty).

2 findings from 1 review

Inhaled steroids vs systemic steroids

Diastolic blood pressure > 95th percentile at 7 years · Neonates with developing BPD

Inhaled steroids probably leads to lower diastolic blood pressure > 95th percentile at 7 years compared with systemic steroids (moderate certainty).

1 finding from 1 review

Inhaled steroids vs systemic steroids

General conceptual ability (GCA) score at 7 years The test has a standardisation mean of 100 and SD of 15 · Neonates with developing BPD

Inhaled steroids showed no clear difference in general conceptual ability (GCA) score at 7 years The test has a… compared with systemic steroids (moderate certainty).

1 finding from 1 review

Inhaled steroids vs systemic steroids

Systolic blood pressure > 95th percentile at 7 years · Neonates with developing BPD

Inhaled steroids showed no clear difference in systolic blood pressure > 95th percentile at 7 years compared with systemic steroids (moderate certainty).

1 finding from 1 review