Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,532 questions · 2,642 findings · 483 reviews · Headline outcomes only

No studies found 534 · 20.2%GRADE not reported 82 · 3.1%Very low 641 · 24.3%Low 807 · 30.5%Moderate 472 · 17.9%High 106 · 4%

Discontinuation with high‐intensity psychological interventions vs continuation

Risk of relapse (as defined by study authors) (HR) · participants with long‐term antidepressants for depressive disorders

Discontinuation with high‐intensity psychological interventions showed no clear difference in risk of relapse (as defined by study authors) (HR) compared with continuation (low certainty).

1 finding from 1 review

Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention

Change in visual loss associated with PSR: visual loss is defined by the deterioration of visual acuity of 3 lines or more with the Snellen chart · type 1 or type 2 diabetics

It is very uncertain whether blood pressure intervention/intensive blood pressure intervention changes visual acuity (loss of 3 lines or more) by 5 years compared with placebo/standard blood pressure intervention (very low certainty).

1 finding from 1 review

Transcutaneous electrical nerve stimulation (TENS) and standard urotherapy vs pelvic floor muscle training (PFMT) with electromyographic biofeedback and standard urotherapy

Resolution of daytime urinary incontinence · children aged 5 to 16 years with daytime urinary incontinence

It is very uncertain whether transcutaneous electrical nerve stimulation (TENS) and standard… changes resolution of daytime urinary incontinence compared with pelvic floor muscle training (PFMT) with electromyographic… (very low certainty).

1 finding from 1 review

Transcutaneous electrical nerve stimulation (TENS) and standard urotherapy vs pelvic floor muscle training (PFMT) with electromyographic biofeedback and standard urotherapy

Objective measurement of volume of incontinent episodes · children aged 5 to 16 years with daytime urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review