Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

880 questions · 912 findings · 126 reviews · Headline outcomes only

No studies found 143 · 15.7%GRADE not reported 38 · 4.2%Very low 250 · 27.4%Low 253 · 27.7%Moderate 168 · 18.4%High 60 · 6.6%

Warm compresses vs control (hands off or no warm compress)

Intact perineum · pregnant women expecting a vaginal birth, singleton vertex presentation at term, with no medical complications

Warm compresses showed no clear difference in intact perineum compared with control (hands off or no warm compress) (moderate certainty).

1 finding from 1 review

Warm compresses vs control (hands off or no warm compress)

Perineal trauma requiring suturing · pregnant women expecting a vaginal birth, singleton vertex presentation at term, with no medical complications

It is very uncertain whether warm compresses changes perineal trauma requiring suturing compared with control (hands off or no warm compress) (very low certainty).

1 finding from 1 review

Warm compresses vs control (hands off or no warm compress)

1st degree tear · pregnant women expecting a vaginal birth, singleton vertex presentation at term, with no medical complications

It is very uncertain whether warm compresses changes 1st degree tear compared with control (hands off or no warm compress) (very low certainty).

1 finding from 1 review

Combinations of antipsychotic drugs vs single antipsychotic drugs

Clinical response: No clinically important response ‐ as defined by each of the studies · schizophrenia or related disorders

It is very uncertain whether combinations of antipsychotic drugs changes clinical response: No clinically important response ‐ as defined by… compared with single antipsychotic drugs (very low certainty).

1 finding from 1 review

Combinations of antipsychotic drugs vs single antipsychotic drugs

Adverse events: Serious event or requiring discontinuation · schizophrenia or related disorders

It is very uncertain whether combinations of antipsychotic drugs changes adverse events: Serious event or requiring discontinuation compared with single antipsychotic drugs (very low certainty).

1 finding from 1 review

Foley catheter vs intravenous (IV) oxytocin

Vaginal delivery not achieved within 24 hours · pregnant women with a previous low transverse caesarean section, singleton live pregnancy with cephalic presentation, period of gestation…

Foley catheter showed no clear difference in vaginal delivery not achieved within 24 hours compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Foley catheter vs intravenous (IV) oxytocin

Uterine hyperstimulation with fetal heart rate changes · pregnant women with a previous low transverse caesarean section, singleton live pregnancy with cephalic presentation, period of gestation…

Foley catheter showed no clear difference in uterine hyperstimulation with fetal heart rate changes compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Foley catheter vs intravenous (IV) oxytocin

Caesarean section · pregnant women with a previous low transverse caesarean section, singleton live pregnancy with cephalic presentation, period of gestation…

Foley catheter showed no clear difference in caesarean section compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review