Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,413 questions · 2,602 findings · 93 reviews · Oral Health

No studies found 452 · 17.4%GRADE not reported 1,582 · 60.8%Very low 392 · 15.1%Low 122 · 4.7%Moderate 53 · 2%High 1 · 0%

Laminar air flow with HEPA filter vs Without laminar flow or filter

Reduction in level of contamination in aerosols (CFU per cubic feet/min/patient) using Reyniers slit sampler 30 inches (76 cm) from floor · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether laminar air flow with HEPA filter changes reduction in level of contamination in aerosols (CFU per cubic… compared with without laminar flow or filter (very low certainty).

1 finding from 1 review

Rubber dam vs No rubber dam

Reduction in level of contamination in aerosols (CFU) during restorative procedures at operator's left ear (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

Rubber dam showed no clear difference in reduction in level of contamination in aerosols (CFU) during… compared with no rubber dam; GRADE not reported.

1 finding from 1 review

Counter-stimulation or distraction vs Conventional treatment

Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Clobetasol propionate ointment vs Clobetasol propionate 0.025% ointment

Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Clobetasol propionate 0.05% ointment showed no clear difference in clinical score compared with clobetasol propionate 0.025% ointment (low certainty).

1 finding from 1 review

Topical triamcinolone acetonide vs Topical ciclosporin

Pain (mean VAS score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Topical triamcinolone acetonide showed no clear difference in pain (mean VAS score) compared with topical ciclosporin; GRADE not reported.

1 finding from 1 review

Counter-stimulation or distraction vs Conventional treatment

Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Camouflage syringe vs Conventional syringe

Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Any method, procedure or policy to reduce contaminated aerosols in dental clinics vs Any other method, no treatment or combination of methods

Reduction in volume of contaminated aerosols in the operative environment · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental laboratory staff, dental…

The review found no eligible studies for this question.

1 finding from 1 review

Electrical counter-stimulation device (DentalVibe) vs Conventional treatment (no stimulation)

Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Clobetasol propionate ointment vs Clobetasol propionate 0.025% ointment

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate 0.05% ointment changes clinical resolution compared with clobetasol propionate 0.025% ointment (very low certainty).

1 finding from 1 review

Counter-stimulation or distraction vs Conventional treatment

Adverse effects: pain on injection (solution deposition), Heft-Parker VAS 0-170 mm · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

Counter-stimulation or distraction led to lower pain on injection (Wong-Baker Faces / TPPPS / FPS-R, after LA) compared with conventional treatment; GRADE not reported.

1 finding from 1 review

Pre-cooling of the injection site vs Conventional treatment

Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Video modelling acclimatisation vs Acclimatisation in clinic (tell-show-do)

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA: pain-related behaviour during LA (negative vs positive behaviour; Frankl Behaviour Rating Scale) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether video modelling acclimatisation changes self- or observational assessment of intraoperative… compared with acclimatisation in clinic (tell-show-do) (very low certainty).

1 finding from 1 review

Topical clobetasol propionate vs Topical tacrolimus

Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical clobetasol propionate changes pain resolution compared with topical tacrolimus (very low certainty).

1 finding from 1 review

Intralesional betamethasone vs intralesional injections of triamcinolone acetonide

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Intralesional betamethasone showed no clear difference in pain (mean score) compared with intralesional triamcinolone acetonide (low certainty).

1 finding from 1 review

Camouflage syringe vs Conventional syringe

Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Topical clobetasol propionate vs Topical ciclosporin

Adverse effects · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical clobetasol propionate changes adverse effects compared with topical ciclosporin (very low certainty).

1 finding from 1 review