Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,793 questions · 1,866 findings · 339 reviews

No studies found 245 · 13.1%GRADE not reported 142 · 7.6%Very low 612 · 32.8%Low 513 · 27.5%Moderate 305 · 16.3%High 49 · 2.6%

Open surgery by transverse incision of the skin in the distal palmar crease vs open surgery

Pain (short‐term) Not measured · patients with trigger finger

The review found no eligible studies for this question.

3 findings from 1 review

Noradrenaline reuptake inhibitors vs placebo

Mental state: significant response or improvement in negative symptoms (PANSS negative subscale, high = worse) ‐ short term (12 weeks) · adults with schizophrenia

It is very uncertain whether noradrenaline reuptake inhibitors changes mental state: significant response or improvement in negative… compared with placebo (very low certainty).

1 finding from 1 review

Noradrenaline reuptake inhibitors vs placebo

Clinical global response: significant response or improvement in global status (CGI‐S, high = worse) ‐ short term (4 weeks) · adults with schizophrenia

It is very uncertain whether noradrenaline reuptake inhibitors changes clinical global response: significant response or improvement in… compared with placebo (very low certainty).

1 finding from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Depressive symptoms · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care showed no clear difference in self‐reported depressive symptoms short term (up to 6 months) ‐ BDI… compared with usual care alone (moderate certainty).

4 findings from 1 review
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Psychotherapy as an adjunct to usual care vs usual care

> 50% reduction in depressive symptoms · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in depressive symptoms from baseline) short… compared with usual care alone (low certainty).

1 finding from 1 review

Early intervention (mobilization or active exercise) vs usual care

Physical performance · critically ill, mechanically ventilated adults
2 findings from 1 review

Information, feedback, and/or counselling vs information only or no intervention

Mean difference in time in sitting bouts lasting 30 minutes or more, short‐term · employees who sit at work
2 findings from 1 review