Findings

What do systematic reviews say?

584 questions · 593 findings · 51 reviews · Airways

No studies found 37 · 6.2%GRADE not reported 40 · 6.7%Very low 44 · 7.4%Low 172 · 29%Moderate 232 · 39.1%High 68 · 11.5%

Tremor · patients with adults with acute asthma

Aminophylline showed no clear difference in tremor compared with placebo (low certainty).

1 finding from 1 review

Vomiting · patients with adults with acute asthma

Aminophylline probably leads to higher vomiting compared with placebo (moderate certainty).

1 finding from 1 review

Addition of intravenous aminophylline to inhaled beta₂‐agonists in adults with acute asthma 2012 · Cochrane Headline outcomes only
OR 4.21 [2.2, 8.07]
7 studies · 321 participants
Moderate

Arrhythmia/palpitations · patients with adults with acute asthma

Aminophylline probably leads to higher arrhythmia/palpitations compared with placebo (moderate certainty).

1 finding from 1 review

Addition of intravenous aminophylline to inhaled beta₂‐agonists in adults with acute asthma 2012 · Cochrane Headline outcomes only
OR 3.02 [1.15, 7.9]
6 studies · 249 participants
Moderate

Convulsions · patients with adults with acute asthma

1 finding from 1 review

Addition of intravenous aminophylline to inhaled beta₂‐agonists in adults with acute asthma 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Moderate