Caries prevention (preventive fraction, SDF vs GIC+5% fluoride varnish) · intellectually disabled individuals with caries in permanent posterior teeth
SDF had a 45% preventative fraction versus glass ionomer cement plus fluoride varnish; no pooled estimate or GRADE rating was reported.
1 finding from 1 review
restoration and caries status · children with caries in permanent molars
The review reported SDF was beneficial for arresting caries; no effect estimate or GRADE rating was reported.
1 finding from 1 review
Root carious lesions prevention · Older adults with root caries (community-dwelling or residential elders)
In elders, sodium fluoride varnish gave a 64% prevented fraction for root caries vs water, lower than SDF (71%) (p<0.01; ungraded).
1 finding from 1 review
Projected Significant Caries (SiC) index · Alaska Native children (below age 18)
A simulation projected a 50% drop in the Significant Caries index for children (12.3 to 6.1) under the PDHA model (certainty not graded).
2 findings from 1 review
Projected proportion of caries-free children (5-18 years) · Alaska Native children (below age 18)
A simulation projected 0% of children aged 5-18 would be caries-free under the baseline scenario (certainty not graded).
3 findings from 1 review
Difference in sensitivity · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)
Imaging had lower sensitivity than visual classification in the fully within-person analysis.
1 finding from 1 review
Difference in specificity · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)
Imaging and visual classification had similar specificity in the fully within-person analysis.
1 finding from 1 review
Composite: Preference for replacement over repair - Scenario 3: secondary caries · Dentists managing a defective direct resin composite restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
Subgroup (Continent: Africa): pooled preference was replacement over repair for a defective composite restoration with secondary caries (RR 4.62); significant continental variation, p < 0.001.
5 findings from 1 review
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · Continent: Africa
RR 4.62 [3.64, 5.86]
2 studies · 339 participants
GRADE not reported
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · Overall (all 21 countries pooled)
RR 2.43 [1.87, 3.16]
21 studies · 3680 participants
GRADE not reported
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · Continent: Europe
RR 3.07 [2.41, 3.89]
6 studies · 1075 participants
GRADE not reported
Show 2 more findings
Composite: Preference for replacement over repair - Scenario 2: loss of dental hard substance adjacent to the restoration · Dentists managing a defective direct resin composite restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
For a defective composite restoration with loss of dental hard substance adjacent to the restoration, surveyed dentists most often preferred repair over replacement (pooled RR 0.75; p = 0.004); ungraded.
1 finding from 1 review
Absence of secondary caries · Children receiving dental restorations (aged 4-11 years; primary teeth; Class I/II/V cavities)
Ion-releasing and composite restorations show no significant difference in absence of secondary caries in children (high certainty).
1 finding from 1 review
Amalgam: Preference for replacement over repair - Scenario 2: loss of dental hard substance adjacent to the restoration · Dentists managing a defective direct amalgam restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
For a defective amalgam restoration with loss of dental hard substance adjacent to the restoration, surveyed dentists most often preferred replacement over repair (pooled RR 4.70; p < 0.001); ungraded.
1 finding from 1 review
Amalgam: Preference for replacement over repair - Scenario 3: secondary caries · Dentists managing a defective direct amalgam restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
For a defective amalgam restoration with secondary caries, surveyed dentists most often preferred replacement over repair (pooled RR 6.94; p < 0.001); ungraded.
1 finding from 1 review
Secondary caries · Patients requiring dental restoration; permanent teeth
Over 1 year in permanent teeth, the effect of ACTIVA versus GIC on secondary caries is very uncertain (RR 22.80, 95% CI 0.89-584.17; very low certainty).
1 finding from 1 review
Secondary caries · Patients requiring dental restoration; permanent teeth
Over 1 year in permanent teeth, secondary caries did not differ significantly between RMGIC and GIC (RR 1.82, 95% CI 0.45-7.28; low certainty).
2 findings from 1 review
Secondary caries · Patients requiring dental restoration; permanent teeth
Over 1 year in permanent teeth, resin composite showed no statistically significant difference in secondary caries versus GIC (RR 3.05, 95% CI 0.95-9.79; low certainty).
2 findings from 1 review
Secondary caries · Patients requiring dental restoration; deciduous (primary) teeth
Over 2 or more years in deciduous teeth, GIC probably had a higher risk of secondary caries than RMGIC (RR 1.92, 95% CI 1.03-3.56; moderate certainty).
1 finding from 1 review
Secondary caries · Patients requiring dental restoration; permanent teeth
Over 2 or more years in permanent teeth, the effect of compomer versus GIC on secondary caries is very uncertain (RR 3.20, 95% CI 0.59-17.33; very low certainty).
1 finding from 1 review
Secondary caries · Patients requiring dental restoration; deciduous (primary) teeth
In deciduous teeth at 1 year, pooled bioactive materials (RMGIC and compomer) showed no significant difference from resin composite in secondary caries (RR 0.54, 95% CI 0.07-4.10; ungraded).
1 finding from 1 review
Secondary caries · Patients requiring dental restoration; deciduous (primary) teeth
Over 2 or more years in deciduous teeth, secondary caries did not differ significantly between compomer and RMGIC (RR 1.68, 95% CI 0.87-3.25; low certainty).
1 finding from 1 review
Secondary caries · Patients requiring dental restoration; permanent teeth
Over 2 or more years in permanent teeth, secondary caries did not differ significantly between fluoride-containing amalgam and GIC (RR 0.95, 95% CI 0.45-2.00; low certainty).
1 finding from 1 review