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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,558 questions in 115 reviews · Vascular

current versions
No studies 346 · 22.2%Ungraded 90 · 5.8%Very low 281 · 18%Low 477 · 30.6%Moderate 313 · 20.1%High 51 · 3.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Gait training protocol focused on impairment level vs gait training protocol focused on task level
Phantom limb pain frequency · people with transtibial amputation due to peripheral arterial disease or diabetes
Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial… (2023) · Cochrane
no estimate extractedNRNo studies
Motor imaging vs usual care
Adverse events · people with transtibial amputation due to peripheral arterial disease or diabetes
Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial… (2023) · Cochrane
no estimate extractedNRNo studies
Motor imaging vs usual care
Mortality – all causes · people with transtibial amputation due to peripheral arterial disease or diabetes
Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial… (2023) · Cochrane
no estimate extractedNRNo studies
Motor imaging vs usual care
Quality of life · people with transtibial amputation due to peripheral arterial disease or diabetes
Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial… (2023) · Cochrane
no estimate extractedNRNo studies
Motor imaging vs usual care
Mobility assessment · people with transtibial amputation due to peripheral arterial disease or diabetes
Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial… (2023) · Cochrane
no estimate extracted1 study · 8 participantsVery low
Motor imaging vs usual care
Phantom limb pain frequency · people with transtibial amputation due to peripheral arterial disease or diabetes
Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial… (2023) · Cochrane
no estimate extractedNRNo studies
Gait training protocol focused on impairment level vs gait training protocol focused on task level
Prosthesis use · people with transtibial amputation due to peripheral arterial disease or diabetes
Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial… (2023) · Cochrane
no estimate extracted1 study · 22 participantsUngraded
Gait training protocol focused on impairment level vs gait training protocol focused on task level
Adverse events – pain · people with transtibial amputation due to peripheral arterial disease or diabetes
Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial… (2023) · Cochrane
no estimate extracted1 study · 22 participantsVery low
Gait training protocol focused on impairment level vs gait training protocol focused on task level
Mortality – all cause · people with transtibial amputation due to peripheral arterial disease or diabetes
Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial… (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)
Limb salvage rate · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
RR 0.84 [0.49, 1.45]2 studies · 936 participantsLow
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (long term)
Adverse events resulting from DUS surveillance · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (long term)
All‐cause mortality · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (long term)
Functional walking ability · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (long term)
Clinical severity scales · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (long term)
Quality of life scores · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)
Vessel or graft secondary patency · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
RR 0.92 [0.67, 1.26]3 studies · 1092 participantsLow
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)
Adverse events resulting from DUS surveillance · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)
All‐cause mortality · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
RR 1.11 [0.7, 1.74]1 study · 594 participantsLow
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)
Functional walking ability · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)
Clinical severity scales · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)
Quality of life scores · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extracted1 study · 594 participantsLow
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (long term)
Limb salvage rate · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
no estimate extractedNRNo studies
Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (long term)
Vessel or graft secondary patency · people who underwent a lower limb revascularisation
Duplex ultrasound for surveillance of lower limb revascularisation (2023) · Cochrane
RR 0.83 [0.19, 3.51]1 study · 156 participantsLow
Primary treatment with intravenous immunoglobulin (IVIG) vs acetylsalicylic acid (ASA)
Incidence of CAAs (up to 30 days) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
OR 0.6 [0.41, 0.87]11 studies · 1437 participantsModerate
Primary treatment with intravenous immunoglobulin (IVIG) vs different infusion regimens of IVIG
Acute coronary syndrome (such as MI or coronary thrombus) (up to 7 weeks) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extractedNRNo studies
Primary treatment with intravenous immunoglobulin (IVIG) vs different infusion regimens of IVIG
Duration of fever (days) (acute phase) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extracted4 studies · 992 participantsLow
Primary treatment with intravenous immunoglobulin (IVIG) vs different infusion regimens of IVIG
Need for additional treatment (up to 6 months) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
OR 0.29 [0.1, 0.88]4 studies · 1125 participantsLow
Primary treatment with intravenous immunoglobulin (IVIG) vs different infusion regimens of IVIG
Length of hospital stay (days) (up to 28 days) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extracted3 studies · 752 participantsLow
Primary treatment with intravenous immunoglobulin (IVIG) vs different infusion regimens of IVIG
Mortality (all‐cause) (up to 7 weeks) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extracted1 study · 549 participantsModerate
Primary treatment with intravenous immunoglobulin (IVIG) vs prednisolone
Incidence of CAAs (acute phase) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
OR 0.6 [0.24, 1.48]2 studies · 140 participantsVery low
Primary treatment with intravenous immunoglobulin (IVIG) vs prednisolone
Incidence of any adverse effects after treatment initiation (up to 3 months) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
OR 4.18 [0.19, 89.48]1 study · 90 participantsLow
Primary treatment with intravenous immunoglobulin (IVIG) vs prednisolone
Acute coronary syndrome (such as MI or coronary thrombus) (up to 3 months) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extracted1 study · 90 participantsLow
Primary treatment with intravenous immunoglobulin (IVIG) vs prednisolone
Duration of fever (days) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extracted2 studies · 140 participantsVery low
Primary treatment with intravenous immunoglobulin (IVIG) vs prednisolone
Need for additional treatment · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extractedNRNo studies
Primary treatment with intravenous immunoglobulin (IVIG) vs acetylsalicylic acid (ASA)
Incidence of any adverse effects after treatment initiation (from 30 days to 30 months) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
OR 0.57 [0.17, 1.89]10 studies · 1376 participantsVery low
Primary treatment with intravenous immunoglobulin (IVIG) vs prednisolone
Length of hospital stay (days) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extractedNRNo studies
Primary treatment with intravenous immunoglobulin (IVIG) vs prednisolone
Mortality (all‐cause) (up to 30 days) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extracted1 study · 90 participantsLow
Primary treatment with intravenous immunoglobulin (IVIG) vs acetylsalicylic acid (ASA)
Acute coronary syndrome (such as MI or coronary thrombus) (to 30 months) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extracted2 studies · 202 participantsLow
Primary treatment with intravenous immunoglobulin (IVIG) vs acetylsalicylic acid (ASA)
Duration of fever (days) (acute phase) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extracted3 studies · 307 participantsModerate
Primary treatment with intravenous immunoglobulin (IVIG) vs acetylsalicylic acid (ASA)
Need for additional treatment (up to 30 or 60 days) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
OR 0.27 [0.05, 1.57]3 studies · 272 participantsLow
Primary treatment with intravenous immunoglobulin (IVIG) vs acetylsalicylic acid (ASA)
Length of hospital stay (days) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extractedNRNo studies
Primary treatment with intravenous immunoglobulin (IVIG) vs acetylsalicylic acid (ASA)
Mortality (all‐cause) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
no estimate extractedNRLow
Primary treatment with intravenous immunoglobulin (IVIG) vs different infusion regimens of IVIG
Incidence of CAAs (up to 30 days) · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
OR 0.6 [0.4, 0.89]8 studies · 1824 participantsModerate
Primary treatment with intravenous immunoglobulin (IVIG) vs different infusion regimens of IVIG
Incidence of any adverse effects after treatment initiation ( · people undergoing initial treatment for KD
Intravenous immunoglobulin for the treatment of Kawasaki disease (2023) · Cochrane
OR 1.11 [0.52, 2.37]6 studies · 1659 participantsLow
Anticoagulant vs placebo or no treatment
All‐cause mortality · non‐hospitalised people with COVID‐19
Prophylactic anticoagulants for non‐hospitalised people with COVID‐19 (2023) · Cochrane
RR 0.36 [0.04, 3.61]5 studies · 1777 participantsLow
Anticoagulant vs different dose of the same anticoagulant
Major bleeding · non‐hospitalised people with COVID‐19
Prophylactic anticoagulants for non‐hospitalised people with COVID‐19 (2023) · Cochrane
no estimate extracted1 study · 278 participantsModerate
Anticoagulant vs different dose of the same anticoagulant
Deep vein thrombosis · non‐hospitalised people with COVID‐19
Prophylactic anticoagulants for non‐hospitalised people with COVID‐19 (2023) · Cochrane
no estimate extractedNRNo studies
Anticoagulant vs different dose of the same anticoagulant
Pulmonary embolism · non‐hospitalised people with COVID‐19
Prophylactic anticoagulants for non‐hospitalised people with COVID‐19 (2023) · Cochrane
no estimate extractedNRNo studies
Anticoagulant vs different dose of the same anticoagulant
Need for hospitalisation · non‐hospitalised people with COVID‐19
Prophylactic anticoagulants for non‐hospitalised people with COVID‐19 (2023) · Cochrane
RR 1.89 [0.17, 20.58]1 study · 278 participantsLow
Anticoagulant vs different dose of the same anticoagulant
Adverse events (minor bleeding) · non‐hospitalised people with COVID‐19
Prophylactic anticoagulants for non‐hospitalised people with COVID‐19 (2023) · Cochrane
RR 0.47 [0.09, 2.54]1 study · 278 participantsLow