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What do systematic reviews say?

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Evidence found and GRADE certainty

766 questions · 806 findings · 76 reviews · ENT

No studies found 293 · 36.4%GRADE not reported 6 · 0.7%Very low 244 · 30.3%Low 170 · 21.1%Moderate 85 · 10.5%High 8 · 1%

Intratympanic corticosteroids vs placebo/no treatment

Improvement in vertigo frequency · Ménière’s disease

Intratympanic corticosteroids showed no clear difference in improvement in vertigo frequency compared with placebo/no treatment (low certainty).

2 findings from 1 review

Intratympanic corticosteroids vs placebo/no treatment

Change in vertigo frequency · Ménière’s disease
3 findings from 1 review

Intratympanic gentamicin vs no treatment/placebo

Improvement in vertigo frequency · Ménière’s disease

It is very uncertain whether intratympanic gentamicin changes improvement in vertigo frequency compared with no treatment/placebo (very low certainty).

2 findings from 1 review