What do systematic reviews say?

Modified natural cycle FET (HCG trigger) vs HT + GnRHa FET

The review found no eligible studies for this question.

• Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Modified natural cycle FET (HCG trigger) vs HT + GnRHa FET

The review found no eligible studies for this question.

• Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Human chorionic gonadotropin (hCG) injection vs no treatment

It is very uncertain whether human chorionic gonadotropin (hCG) injection changes clinical pregnancy rate compared with no treatment (very low certainty).

• Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
  RR 0.93 [0.4, 2.13]
  1 study · 130 participants
  Very low

Human chorionic gonadotropin (hCG) injection vs no treatment

It is very uncertain whether human chorionic gonadotropin (hCG) injection changes multiple pregnancy rate compared with no treatment (very low certainty).

• Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
  RR 1.03 [0.22, 4.92]
  1 study · 130 participants
  Very low

Suction curettage under hysteroscopy vs under ultrasonography

• Interventions for non‐tubal ectopic pregnancy 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 66 participants
  Very low

UAE/UACE vs MTX

The review found no eligible studies for this question.

• Interventions for non‐tubal ectopic pregnancy 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antioestrogen plus medical adjunct vs antioestrogen

• Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

GnRH agonists vs HCG

GnRH agonist probably leads to lower live birth compared with HCG (moderate certainty).

• Gonadotropin‐releasing hormone agonist versus HCG for oocyte triggering in antagonist‐assisted reproductive technology 2014 · Cochrane Headline outcomes only
  OR 0.47 [0.31, 0.7]
  5 studies · 532 participants
  Moderate

GnRH agonists vs HCG

GnRH agonist probably leads to lower OHSS (mild, moderate or severe): overall risk compared with HCG (moderate certainty).

• Gonadotropin‐releasing hormone agonist versus HCG for oocyte triggering in antagonist‐assisted reproductive technology 2014 · Cochrane Headline outcomes only
  OR 0.15 [0.05, 0.47]
  8 studies · 989 participants
  Moderate

GnRH agonists vs HCG

GnRH agonist probably leads to lower OHSS (moderate or severe): overall risk compared with HCG (moderate certainty).

• Gonadotropin‐releasing hormone agonist versus HCG for oocyte triggering in antagonist‐assisted reproductive technology 2014 · Cochrane Headline outcomes only
  OR 0.21 [0.07, 0.66]
  8 studies · 989 participants
  Moderate

GnRH agonists vs HCG

GnRH agonist probably leads to lower OHSS (mild, moderate or severe) in women at high risk of OHSS compared with HCG (moderate certainty).

• Gonadotropin‐releasing hormone agonist versus HCG for oocyte triggering in antagonist‐assisted reproductive technology 2014 · Cochrane Headline outcomes only
  OR 0.06 [0.01, 0.34]
  3 studies · 212 participants
  Moderate

GnRH agonists vs HCG

GnRH agonist may leads to lower ongoing pregnancy compared with HCG (low certainty).

• Gonadotropin‐releasing hormone agonist versus HCG for oocyte triggering in antagonist‐assisted reproductive technology 2014 · Cochrane Headline outcomes only
  OR 0.7 [0.54, 0.91]
  11 studies · 1198 participants
  Low

GnRH agonists vs HCG

GnRH agonist probably leads to higher miscarriage compared with HCG (moderate certainty).

• Gonadotropin‐releasing hormone agonist versus HCG for oocyte triggering in antagonist‐assisted reproductive technology 2014 · Cochrane Headline outcomes only
  OR 1.74 [1.1, 2.75]
  11 studies · 1198 participants
  Moderate

Coasting vs follicle stimulating hormone administration at time of hCG

It is very uncertain whether coasting changes OHSS compared with follicle stimulating hormone administration at time of hCG (very low certainty).

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  OR 43.74 [2.54, 754.58]
  1 study · 102 participants
  Very low

Coasting vs follicle stimulating hormone administration at time of hCG

The review found no eligible studies for this question.

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Coasting vs follicle stimulating hormone administration at time of hCG

Coasting showed no clear difference in clinical Pregnancy compared with follicle stimulating hormone administration at time of hCG (low certainty).

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  OR 0.92 [0.43, 2.01]
  1 study · 102 participants
  Low

Coasting vs follicle stimulating hormone administration at time of hCG

The review found no eligible studies for this question.

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Coasting vs follicle stimulating hormone administration at time of hCG

The review found no eligible studies for this question.

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Natural cycle FET vs modified natural cycle FET (HCG trigger)

It is very uncertain whether natural cycle FET changes miscarriage rate per woman compared with modified natural cycle FET (HCG trigger) (very low certainty).

• Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
  OR 0.2 [0.01, 4.13]
  1 study · 168 participants
  Very low

Natural cycle FET vs modified natural cycle FET (HCG trigger)

It is very uncertain whether natural cycle FET changes ongoing pregnancy rate per woman compared with modified natural cycle FET (HCG trigger) (very low certainty).

• Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
  OR 2.44 [1.03, 5.76]
  1 study · 168 participants
  Very low