Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

48 questions · 217 findings · 4 reviews · All outcomes

No studies found 0 · 0%GRADE not reported 217 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

T allele of AMELX rs6639060 vs C allele of AMELX rs6639060

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between T allele vs C allele of AMELX rs6639060 and dental caries susceptibility (T vs C model: OR 1.08, 95% CI 0.63-1.85) in the Ethnicity: Caucasian subgroup; certainty not graded.

3 findings from 1 review

TT genotype of AMELX rs2106416 vs CC genotype of AMELX rs2106416

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between TT genotype vs CC genotype of AMELX rs2106416 and dental caries susceptibility (TT vs CC model: OR 1.83, 95% CI 0.47-7.06); certainty not graded.

3 findings from 1 review

TT genotype of ENAM rs3796703 vs CC + CT genotype of ENAM rs3796703

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between TT genotype vs CC + CT genotype of ENAM rs3796703 and dental caries susceptibility (TT vs CC + CT model: OR 2.90, 95% CI 0.92-9.12); certainty not graded.

3 findings from 1 review

T allele of AMELX rs2106416 vs C allele of AMELX rs2106416

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between T allele vs C allele of AMELX rs2106416 and dental caries susceptibility (T vs C model: OR 0.59, 95% CI 0.16-2.11); certainty not graded.

3 findings from 1 review

CT genotype of ENAM rs3796703 vs CC genotype of ENAM rs3796703

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between CT genotype vs CC genotype of ENAM rs3796703 and dental caries susceptibility (CT vs CC model: OR 0.89, 95% CI 0.23-3.48) in the Ethnicity: Asian subgroup; certainty not graded.

3 findings from 1 review

TT genotype of ENAM rs3796703 vs CC genotype of ENAM rs3796703

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between TT genotype vs CC genotype of ENAM rs3796703 and dental caries susceptibility (TT vs CC model: OR 5.22, 95% CI 0.25-108.96) in the Ethnicity: Asian subgroup; certainty not graded.

3 findings from 1 review

CT + TT genotype (T-allele carriers) of ENAM rs3796703 vs CC genotype of ENAM rs3796703

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between CT + TT genotype (T-allele carriers) vs CC genotype of ENAM rs3796703 and dental caries susceptibility (CT + TT vs CC model: OR 0.90, 95% CI 0.23-3.63); certainty not graded.

3 findings from 1 review

TT genotype of AMELX rs6639060 vs CC + CT genotype of AMELX rs6639060

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between TT genotype vs CC + CT genotype of AMELX rs6639060 and dental caries susceptibility (TT vs CC + CT model: OR 1.00, 95% CI 0.42-2.39) in the Ethnicity: Caucasian subgroup; certainty not graded.

3 findings from 1 review