Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

163 questions · 170 findings · 11 reviews · Gynaecology and Fertility

No studies found 60 · 35.3%GRADE not reported 4 · 2.4%Very low 53 · 31.2%Low 36 · 21.2%Moderate 15 · 8.8%High 2 · 1.2%

Raloxifene vs placebo

Adverse events ‐ pelvic pain · women with endometriosis, following complete surgical excision of lesions

It is very uncertain whether raloxifene changes adverse events ‐ pelvic pain compared with placebo (very low certainty).

1 finding from 1 review

Raloxifene vs placebo

Adverse events ‐ ovarian cyst · women with endometriosis, following complete surgical excision of lesions

It is very uncertain whether raloxifene changes adverse events ‐ ovarian cyst compared with placebo (very low certainty).

1 finding from 1 review

Raloxifene vs placebo

Adverse events ‐ depression · women with endometriosis, following complete surgical excision of lesions

It is very uncertain whether raloxifene changes adverse events ‐ depression compared with placebo (very low certainty).

1 finding from 1 review

Raloxifene vs placebo

Biopsy‐proven recurrence of endometriosis · women with endometriosis, following complete surgical excision of lesions

It is very uncertain whether raloxifene changes biopsy‐proven recurrence of endometriosis compared with placebo (very low certainty).

1 finding from 1 review

LOD vs other surgical interventions

Harms: Adhesions at 6 months ‐ LOD vs THL N of participants: 246 (1 RCT) · Women with symptoms of PCOS

It is very uncertain whether LOD changes harms: Adhesions at 6 months ‐ LOD vs THL N of participants: 246 (1… compared with other surgical interventions (very low certainty).

1 finding from 1 review

LOD vs other surgical interventions

Menstrual regularity at 12 months Laser LOD vs harmonic scalpel N of participants: 34 (1 RCT) · Women with symptoms of PCOS

LOD showed no clear difference in menstrual regularity at 6 months ‐ LOD vs ultrasound‐guided… compared with other surgical interventions (low certainty).

2 findings from 1 review

LOD vs other surgical interventions

Improvement in androgenic symptoms at 6 months (Acne) ‐ LOD vs USS guided N of participants:31 (1 RCT) · Women with symptoms of PCOS

LOD showed no clear difference in improvement in androgenic symptoms at 6 months (Acne) ‐ LOD vs USS… compared with other surgical interventions (low certainty).

1 finding from 1 review

LOD vs other surgical interventions

Improvement in androgenic symptoms at 6 months (Hirsutism) ‐ LOD vs USS‐guided N of participants: 39 (1 RCT) · Women with symptoms of PCOS

LOD showed no clear difference in improvement in androgenic symptoms at 6 months (Hirsutism) ‐ LOD vs… compared with other surgical interventions (low certainty).

1 finding from 1 review