What do systematic reviews say?

Supportive and counselling interventions vs treatment

The review found no eligible studies for this question.

• Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

The review found no eligible studies for this question.

• Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care

Continuous positive airway pressure (CPAP) plus best supportive care may leads to lower time to life‐saving cardiovascular intervention ( compared with best supportive care (low certainty).

• Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Supportive periodontal therapy (SPT) including mechanical debridement vs Monitoring only, or alternative interventions that do not include mechanical debridement

The review found no eligible studies for this question.

• Supportive periodontal therapy (SPT) for maintaining the dentition in adults treated for periodontitis 2018 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Educational intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 1128 participants
  Very low

Behavioural intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 578 participants
  High

Behavioural intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 525 participants
  Moderate

Behavioural intervention vs control

Behavioural intervention leads to higher 3.3 N deemed adherent (≥ four hours/night) compared with control (high certainty).

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  OR 1.7 [1.2, 2.41]
  6 studies · 549 participants
  High

Behavioural intervention vs control

Behavioural intervention leads to lower 3.4 Withdrawal compared with control (high certainty).

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  OR 0.66 [0.44, 0.98]
  10 studies · 939 participants
  High

Behavioural intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 271 participants
  Low

Behavioural intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 89 participants
  Very low

Behavioural intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 228 participants
  Moderate
• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 200 participants
  GRADE not reported

Educational intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 698 participants
  Very low

Educational intervention vs control

It is very uncertain whether educational intervention changes 1.3 N deemed adherent (≥ four hours/night) compared with control (very low certainty).

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  OR 2.58 [1.5, 4.44]
  7 studies · 1019 participants
  Very low

Educational intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 1745 participants
  GRADE not reported

Educational intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 355 participants
  GRADE not reported

Methionine and supportive treatment vs supportive treatment

It is very uncertain whether methionine and supportive treatment changes mortality compared with supportive treatment (very low certainty).

• Interventions for paracetamol (acetaminophen) overdose 2018 · Cochrane Headline outcomes only
  Peto OR 0.14 [0, 6.82]
  1 study · 26 participants
  Very low

Methionine and supportive treatment vs supportive treatment

Methionine and supportive treatment may leads to lower hepatotoxicity compared with supportive treatment (low certainty).

• Interventions for paracetamol (acetaminophen) overdose 2018 · Cochrane Headline outcomes only
  OR 0.05 [0.01, 0.53]
  1 study · 26 participants
  Low

Mixed (BEH/EDU/SUP) intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 4509 participants
  Very low

Mixed (BEH/EDU/SUP) intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 343 participants
  Very low