Composite outcome – non‐randomised studies Composite endpoint of cardiopulmonary arrest, unplanned ICU admission or death per 1000 admitted patients ( · adult on acute hospital wards at risk of clinical deterioration
1 finding from 1 review
AOR 0.85 [0.72, 0.99]
57858 participants
Low
Unplanned ICU admission – non‐randomised trial ( · adult on acute hospital wards at risk of clinical deterioration
2 findings from 1 review
AOR 1.04 [0.89, 1.21]
364094 participants
Low
no estimate extracted
Studies not reported
Very low
ICU readmission – non‐randomised studies · adult on acute hospital wards at risk of clinical deterioration
The review found no eligible studies for this question.
2 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Repeated need for rapid tranquillisation ‐ needing additional injection during 24 hours · patients with psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation ‐ needing additional… compared with COMBINATIONS: b. HALOPERIDOL + LORAZEPAM (very low certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation ‐ more than 1 injection · patients with psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation ‐ more that 1 injection compared with OTHER ANTIPSYCHOTIC: b. CHLORPROMAZINE (very low certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation ‐ more than 1 injection · psychosis‐induced aggression or agitation
HALOPERIDOL probably leads to higher repeated need for rapid tranquillisation ‐ more than 1 injection compared with OTHER ANTIPSYCHOTIC: c. DROPERIDOL (moderate certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation ‐ not reported · patients with psychosis‐induced aggression or agitation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Repeated need for rapid tranquillisation ‐ needing additional benzodiazepine · patients with psychosis‐induced aggression or agitation
HALOPERIDOL showed no clear difference in repeated need for rapid tranquillisation ‐ needing additional… compared with OTHER ANTIPSYCHOTIC: h. RISPERIDONE (low certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation · patients with psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation compared with OTHER ANTIPSYCHOTIC: i. THIOTHIXENE (very low certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation ‐ more than 3 injections · patients with psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation ‐ more than 3 injections compared with OTHER ANTIPSYCHOTIC: k. ZUCLOPENTHIXOL ACETATE (very low certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation ‐ needing additional injection · patients with psychosis‐induced aggression or agitation
HALOPERIDOL may leads to lower repeated need for rapid tranquillisation ‐ needing additional… compared with OTHER ANTIPSYCHOTIC: a. ARIPIPRAZOLE (low certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation ‐ more than 1 injection · patients with psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation more than 1 injection compared with BENZODIAZEPINE: b. LORAZEPAM (very low certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation ‐ not reported · patients with psychosis‐induced aggression or agitation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Neonatal mortality · preterm infants at risk of respiratory distress syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality before hospital discharge · preterm infants at risk of respiratory distress syndrome
It is very uncertain whether surfactant treatment guided by rapid tests for surfactant deficiency changes mortality prior to hospital discharge№ of participants: 562 (3 RCTs) compared with surfactant therapy provided to preterm infants with respiratory… (very low certainty).
1 finding from 1 review
RR 1.25 [0.65, 2.41]
Studies not reported
Very low
Bronchopulmonary dysplasia · preterm infants at risk of respiratory distress syndrome
Surfactant treatment guided by rapid tests for surfactant deficiency showed no clear difference in bronchopulmonary dysplasia№ of participants: 562(3 RCTs) compared with surfactant therapy provided to preterm infants with respiratory… (low certainty).
1 finding from 1 review
RR 0.9 [0.61, 1.32]
Studies not reported
Low
Bronchopulmonary dysplasia or mortality ‐ not reported · preterm infants at risk of respiratory distress syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Surfactant utilization № of participants: 562 (3 RCTs) · preterm infants at risk of respiratory distress syndrome
Surfactant treatment guided by rapid tests for surfactant deficiency showed no clear difference in surfactant utilization № of participants: 562 (3 RCTs) compared with surfactant therapy provided to preterm infants with respiratory… (low certainty).
1 finding from 1 review
RR 0.97 [0.85, 1.11]
Studies not reported
Low
Pneumothorax · preterm infants at risk of respiratory distress syndrome
Surfactant treatment guided by rapid tests for surfactant deficiency showed no clear difference in any pneumothorax№ of participants: 506(2 RCTs) compared with surfactant therapy provided to preterm infants with respiratory… (low certainty).
1 finding from 1 review
RR 0.53 [0.15, 1.92]
Studies not reported
Low
Neurodevelopmental outcomes · preterm infants at risk of respiratory distress syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found