Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

69 questions · 69 findings · 16 reviews · Heart

No studies found 12 · 17.4%GRADE not reported 1 · 1.4%Very low 10 · 14.5%Low 22 · 31.9%Moderate 20 · 29%High 4 · 5.8%

Intervention not reported

ASCVD event, such as fatal or non‐fatal myocardial infarction or stroke. Median · adults older than 18 years, with no restriction regarding presence of ASCVD; participants generally had elevated risk of ASCVD (as…

The intervention showed no clear difference in ASCVD event, such as fatal or non‐fatal myocardial infarction or… (low certainty).

1 finding from 1 review

Intervention not reported

Any investigator‐defined adverse event Median · adults older than 18 years, with no restriction regarding presence of ASCVD; participants generally had elevated risk of ASCVD (as…

The intervention probably leads to higher any investigator‐defined adverse event Median (moderate certainty).

1 finding from 1 review

Intervention not reported

Adherence, variable definitions Median · adults older than 18 years, with no restriction regarding presence of ASCVD; participants generally had elevated risk of ASCVD (as…

The intervention probably leads to higher adherence, variable definitions Median (moderate certainty).

1 finding from 1 review

Intervention not reported

Death at any time · patients with acute coronary syndrome

The intervention may leads to lower death at any time (low certainty).

1 finding from 1 review

Intervention not reported

hour Plasma Creatine Phosphokinase · patients with acute coronary syndrome
1 finding from 1 review

Intervention not reported

hour Plasma Creatine Phosphate · patients with acute coronary syndrome
1 finding from 1 review

Intervention not reported

Maximum Plasma Creatine Phosphate · patients with acute coronary syndrome
1 finding from 1 review