What do systematic reviews say?

Psychological therapies vs SSRI

All psychological therapies showed no clear difference in dropouts for any reason compared with SSRI (low certainty).

• Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
  RR 1.33 [0.8, 2.22]
  6 studies · 334 participants
  Low

Psychological therapies vs SSRI

• Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Psychological therapies vs SSRI

• Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 242 participants
  Moderate

Psychological therapies vs tricyclic antidepressants (TCAs)

All psychological therapies showed no clear difference in short‐term remission compared with tricyclic antidepressants (low certainty).

• Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
  RR 0.82 [0.62, 1.09]
  3 studies · 229 participants
  Low

Psychological therapies vs tricyclic antidepressants (TCAs)

All psychological therapies showed no clear difference in short‐term response compared with tricyclic antidepressants (low certainty).

• Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
  RR 0.75 [0.51, 1.1]
  4 studies · 270 participants
  Low

Psychological therapies vs tricyclic antidepressants (TCAs)

All psychological therapies showed no clear difference in dropouts for any reason compared with tricyclic antidepressants (low certainty).

• Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
  RR 0.83 [0.53, 1.3]
  5 studies · 430 participants
  Low

Psychological therapies vs tricyclic antidepressants (TCAs)

• Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Psychological therapies and co‐intervention vs co‐intervention alone

• Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 114 participants
  Very low

Psychological therapies vs usual care

• Mind and body therapy for fibromyalgia 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Psychological therapies vs usual care

• Mind and body therapy for fibromyalgia 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Psychological therapies vs usual care

• Mind and body therapy for fibromyalgia 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Psychological therapies vs usual care

It is very uncertain whether psychological therapies changes all cause attrition post‐intervention Number of people withdrawing… compared with usual care (very low certainty).

• Mind and body therapy for fibromyalgia 2015 · Cochrane Headline outcomes only
  RR 1.38 [1.12, 1.69]
  Studies not reported
  Very low

Psychological therapies vs usual care

Psychological therapies showed no clear difference in adverse events post‐intervention Number of people reporting an… compared with usual care (low certainty).

• Mind and body therapy for fibromyalgia 2015 · Cochrane Headline outcomes only
  RR 0.38 [0.06, 2.5]
  Studies not reported
  Low

Psychological therapies and/or group programmes vs no treatment or waiting list

• Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 54 participants
  Very low

Psychological therapies and/or group programmes vs active control

• Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 600 participants
  Very low

Psychological therapies and/or group programmes vs active control

• Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 1245 participants
  Low

Psychological therapies and/or group programmes vs active control

• Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 1453 participants
  Very low

Psychological therapies and/or group programmes vs no treatment or waiting list

• Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 285 participants
  Low

Psychological therapies and/or group programmes vs no treatment or waiting list

• Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 285 participants
  Low

Psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up

• Psychological therapies for depression in older adults residing in long‐term care settings 2024 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 195 participants
  Very low