Findings

What do systematic reviews say?

47 questions · 47 findings · 2 reviews

No studies found 16 · 34%GRADE not reported 2 · 4.3%Very low 4 · 8.5%Low 19 · 40.4%Moderate 5 · 10.6%High 1 · 2.1%

Ulcer healing · people with critical limb ischaemia

Iloprost showed no clear difference in ulcer healing compared with PGE1 (low certainty).

1 finding from 1 review

Prostanoids for critical limb ischaemia 2018 · Cochrane Headline outcomes only
RR 1.24 [0.95, 1.63]
1 study · 228 participants
Low

Cardiovascular mortality · people with critical limb ischaemia

1 finding from 1 review

Prostanoids for critical limb ischaemia 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
GRADE not reported

Amputation · people with critical limb ischaemia

The review found no eligible studies for this question.

1 finding from 1 review

Prostanoids for critical limb ischaemia 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Quality of life · people with critical limb ischaemia

The review found no eligible studies for this question.

1 finding from 1 review

Prostanoids for critical limb ischaemia 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adverse events · people with critical limb ischaemia

Clinprost showed no clear difference in adverse events compared with lipo‐PGE1 (moderate certainty).

1 finding from 1 review

Prostanoids for critical limb ischaemia 2018 · Cochrane Headline outcomes only
RR 1.83 [0.56, 5.96]
1 study · 135 participants
Moderate

Rest‐pain relief · people with critical limb ischaemia

Clinprost showed no clear difference in rest‐pain relief compared with lipo‐PGE1 (low certainty).

1 finding from 1 review

Prostanoids for critical limb ischaemia 2018 · Cochrane Headline outcomes only
RR 1.05 [0.58, 1.87]
1 study · 67 participants
Low

Ulcer healing · people with critical limb ischaemia

Clinprost showed no clear difference in ulcer healing compared with lipo‐PGE1 (low certainty).

1 finding from 1 review

Prostanoids for critical limb ischaemia 2018 · Cochrane Headline outcomes only
RR 1.18 [0.74, 1.89]
1 study · 72 participants
Low