Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

63 questions · 66 findings · 10 reviews · Headline outcomes only

No studies found 12 · 18.2%GRADE not reported 3 · 4.5%Very low 15 · 22.7%Low 21 · 31.8%Moderate 14 · 21.2%High 1 · 1.5%

Oral cyclophosphamide vs prednisone or placebo

Adverse events: hypertension with seizures · idiopathic steroid‐resistant nephrotic syndrome in children

It is very uncertain whether oral cyclophosphamide changes adverse events: hypertension with seizures compared with prednisone or placebo (very low certainty).

1 finding from 1 review