Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,368 questions · 1,413 findings · 89 reviews · Common Mental Disorders

No studies found 232 · 16.4%GRADE not reported 82 · 5.8%Very low 395 · 28%Low 331 · 23.4%Moderate 341 · 24.1%High 32 · 2.3%

Intervention not reported

Suicide (Observation period ‐ pre‐intervention: 89 years; postintervention 78.5 years) · adults or children of all ethnicities

The intervention may leads to lower suicide (Observation period ‐ pre‐intervention: 89 years;… (low certainty).

1 finding from 1 review

Antidepressants vs placebo

Depression response (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months

Antidepressants showed no clear difference in depression response (acute, 5 ≤ 12 weeks) compared with placebo (low certainty).

1 finding from 1 review

Antidepressants vs treatment

Depression remission · women of any age, with PND up to 12 months

It is very uncertain whether antidepressants changes depression remission (early phase, < 5 weeks) compared with treatment (very low certainty).

1 finding from 1 review

Antidepressants vs placebo

Depression remission · women of any age, with PND up to 12 months

Antidepressants showed no clear difference in depression remission (acute, 5 ≤ 12 weeks) compared with placebo (low certainty).

1 finding from 1 review

Antidepressants vs any other pharmacological intervention

Depression remission · women of any age, with PND up to 12 months

It is very uncertain whether antidepressants changes depression remission (acute phase, 5 ≤ 12 weeks) compared with any other pharmacological intervention (very low certainty).

2 findings from 1 review