Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

152 questions · 166 findings · 8 reviews · Stroke

No studies found 63 · 38%GRADE not reported 20 · 12%Very low 66 · 39.8%Low 17 · 10.2%Moderate 0 · 0%High 0 · 0%

Movement interventions vs control

Neglect outcomes: effects persisting at least 1 month post intervention · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

The review found no eligible studies for this question.

1 finding from 1 review

Movement interventions vs control

Neglect outcomes: immediate effects · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether movement interventions changes neglect outcomes: immediate effects compared with any control (very low certainty).

1 finding from 1 review

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: meeting study criteria for depression at end of · people with depression after stroke

Pharmacological intervention and non‐invasive brain stimulation… may leads to lower depression: meeting the criteria for depression at end of treatment… compared with a pharmacological intervention and sham stimulation or usual care… (low certainty).

2 findings from 1 review

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke

It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes depression: < 50% reduction in scale scores at end of treatment… compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).

1 finding from 1 review

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: mean scores at end of treatment (secondary outcome) · people with depression after stroke
1 finding from 1 review

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Adverse events: death ‐ at end of treatment (secondary outcome) · people with depression after stroke

It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes adverse events: death (secondary outcome) compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).

1 finding from 1 review

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Adverse events: all ‐ central nervous system events (e.g. headache, seizures) (secondary outcome) · people with depression after stroke

It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes adverse events: all ‐ central nervous system events (e.g. headache,… compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).

1 finding from 1 review

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Adverse events: all ‐ other events ‐ not listed above (e.g. dysuria, neck pain, eye discomfort) (secondary outcome) · people with depression after stroke

It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes adverse events: all ‐ other events ‐ not listed above (e.g.… compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).

1 finding from 1 review

Body awareness interventions vs control

Activities of daily living · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether body awareness interventions changes activities of daily living: effects persisting at least 1 month post… compared with any control (very low certainty).

2 findings from 1 review

Body awareness interventions vs control

Neglect outcomes: effects persisting at least 1 month post intervention · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether body awareness interventions changes neglect outcomes: effects persisting at least 1 month post… compared with any control (very low certainty).

1 finding from 1 review

Body awareness interventions vs control

Neglect outcomes: immediate effects · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether body awareness interventions changes neglect outcomes: immediate effects compared with any control (very low certainty).

1 finding from 1 review

Body awareness interventions vs control

Adverse events · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether body awareness interventions changes adverse events compared with any control (very low certainty).

1 finding from 1 review

Mental function interventions vs control

Activities of daily living · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

The review found no eligible studies for this question.

2 findings from 1 review

Mental function interventions vs control

Neglect outcomes: effects persisting at least 1 month post intervention · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

The review found no eligible studies for this question.

1 finding from 1 review