What do systematic reviews say?

Oxytocin solution vs Normal saline

• Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 167 participants
  Very low

Oxytocin solution vs plasma expander

It is very uncertain whether oxytocin solution changes manual removal of the placenta compared with plasma expander (very low certainty).

• Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
  RR 1.34 [0.97, 1.85]
  1 study · 109 participants
  Very low

Oxytocin solution vs plasma expander

The review found no eligible studies for this question.

• Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oxytocin solution vs plasma expander

It is very uncertain whether oxytocin solution changes severe PPH (≥ 1000 mL) compared with plasma expander (very low certainty).

• Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
  RR 0.96 [0.34, 2.75]
  1 study · 109 participants
  Very low

Oxytocin solution vs plasma expander

The review found no eligible studies for this question.

• Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oxytocin solution vs plasma expander

The review found no eligible studies for this question.

• Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oxytocin solution vs plasma expander

The review found no eligible studies for this question.

• Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oxytocin solution vs plasma expander

The review found no eligible studies for this question.

• Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oxytocin solution vs expectant management

Oxytocin solution may leads to lower manual removal of the placenta compared with expectant management (low certainty).

• Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
  RR 0.73 [0.56, 0.95]
  7 studies · 546 participants
  Low

Oxytocin solution vs expectant management

• Umbilical vein injection for management of retained placenta 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 93 participants
  Very low

Oral misoprostol vs intravenous (IV) oxytocin

Oral misoprostol may leads to lower oxytocin augmentation compared with intravenous oxytocin (low certainty).

• Low‐dose oral misoprostol for induction of labour 2021 · Cochrane Headline outcomes only
  RR 0.12 [0.02, 0.85]
  3 studies · 261 participants
  Low

Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection)

It is very uncertain whether prophylactic oxytocin injection (delivered by community health… changes severe postpartum haemorrhage (> 1000 mL) [ compared with control (no injection) (very low certainty).

• Oxytocin for preventing postpartum haemorrhage (PPH) in non‐facility birth settings 2016 · Cochrane Headline outcomes only
  RR 0.16 [0.02, 1.3]
  1 study · 1569 participants
  Very low

Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection)

• Oxytocin for preventing postpartum haemorrhage (PPH) in non‐facility birth settings 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1586 participants
  Very low

Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection)

• Oxytocin for preventing postpartum haemorrhage (PPH) in non‐facility birth settings 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1586 participants
  Very low

Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection)

Prophylactic oxytocin injection (delivered by community health… may leads to lower postpartum haemorrhage (PPH greater or equal to 500 mL) [ compared with control (no injection) (low certainty).

• Oxytocin for preventing postpartum haemorrhage (PPH) in non‐facility birth settings 2016 · Cochrane Headline outcomes only
  RR 0.48 [0.28, 0.81]
  1 study · 1574 participants
  Low
• Oxytocin for preventing postpartum haemorrhage (PPH) in non‐facility birth settings 2016 · Cochrane Headline outcomes only
  RR 0.49 [0.27, 0.9]
  1 study · 1574 participants
  Low

Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection)

Prophylactic oxytocin injection (delivered by community health… showed no clear difference in transfer or referral to health facility [ compared with control (no injection) (low certainty).

• Oxytocin for preventing postpartum haemorrhage (PPH) in non‐facility birth settings 2016 · Cochrane Headline outcomes only
  RR 0.72 [0.34, 1.56]
  1 study · 1586 participants
  Low

Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection)

Prophylactic oxytocin injection (delivered by community health… showed no clear difference in stillbirths [ compared with control (no injection) (low certainty).

• Oxytocin for preventing postpartum haemorrhage (PPH) in non‐facility birth settings 2016 · Cochrane Headline outcomes only
  RR 1.27 [0.67, 2.4]
  1 study · 2006 participants
  Low

Prophylactic oxytocin injection (delivered by community health officer) vs control (no injection)

Prophylactic oxytocin injection (delivered by community health… showed no clear difference in early infant death (0‐3 days) [ compared with control (no injection) (low certainty).

• Oxytocin for preventing postpartum haemorrhage (PPH) in non‐facility birth settings 2016 · Cochrane Headline outcomes only
  RR 1.03 [0.35, 3.07]
  1 study · 1969 participants
  Low

Summary of findings table ‐ Moxibustion plus usual care vs sham moxibustion plus usual care

The review found no eligible studies for this question.

• Cephalic version by moxibustion for breech presentation 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Moxibustion plus usual care vs usual care

Summary of findings table ‐ Moxibustion plus usual care probably leads to lower use of oxytocin compared with usual care (moderate certainty).

• Cephalic version by moxibustion for breech presentation 2023 · Cochrane Headline outcomes only
  RR 0.28 [0.13, 0.6]
  1 study · 161 participants
  Moderate