Findings

What do systematic reviews say?

54 questions · 57 findings · 6 reviews · Pain, Palliative and Supportive Care

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No studies found 6 · 10.5%GRADE not reported 0 · 0%Very low 30 · 52.6%Low 10 · 17.5%Moderate 7 · 12.3%High 4 · 7%

Celecoxib vs naproxen

Patient Global Impression of Change much or very much improved · children and adolescents with chronic non‐cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for chronic non‐cancer pain in children and adolescents 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Participants with at least 30% or at least 50% reduction in pain · people with cancer pain

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs (NSAIDs) for cancer pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

PGIC much or very much improved · people with cancer pain

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs (NSAIDs) for cancer pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

Pain no worse than mild at one or two weeks (or equivalent) · people with cancer pain

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs (NSAIDs) for cancer pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 415 participants
Very low

Intervention not reported

Serious adverse events · people with cancer pain

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs (NSAIDs) for cancer pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 949 participants
Very low

Intervention not reported

Adverse events · people with cancer pain

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs (NSAIDs) for cancer pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

Withdrawals · people with cancer pain

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs (NSAIDs) for cancer pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

Death · people with cancer pain

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs (NSAIDs) for cancer pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 949 participants
Very low

Intervention not reported

Topical diclofenac gel or solution Clinical success (for example 50% reduction in pain) · adults with chronic musculoskeletal pain (osteoarthritis)

1 finding from 1 review

Topical NSAIDs for chronic musculoskeletal pain in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 2342 participants
Moderate

Intervention not reported

Topical ketoprofen gel Clinical success (for example 50% reduction in pain) · adults with chronic musculoskeletal pain (osteoarthritis)

1 finding from 1 review

Topical NSAIDs for chronic musculoskeletal pain in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 2573 participants
Moderate

Intervention not reported

Topical diclofenac gel or solution Local adverse events · adults with chronic musculoskeletal pain (osteoarthritis)

1 finding from 1 review

Topical NSAIDs for chronic musculoskeletal pain in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
15 studies · 3658 participants
Moderate

Intervention not reported

Topical ketoprofen gel Local adverse events · adults with chronic musculoskeletal pain (osteoarthritis)

1 finding from 1 review

Topical NSAIDs for chronic musculoskeletal pain in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 2621 participants
Moderate

Intervention not reported

Systemic adverse events · adults with chronic musculoskeletal pain (osteoarthritis)

1 finding from 1 review

Topical NSAIDs for chronic musculoskeletal pain in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

Serious adverse events · adults with chronic musculoskeletal pain (osteoarthritis)

1 finding from 1 review

Topical NSAIDs for chronic musculoskeletal pain in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
30 participants
Very low