Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in ascorbic acid compared with placebo or no treatment (low certainty).
Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in dinoprostone (prostaglandin E2 analogue) compared with placebo or no treatment (low certainty).
It is very uncertain whether uterine artery embolization (UAE) changes live birth ‐ UAE versus myomectomy compared with surgery (very low certainty).
It is very uncertain whether any type of in‐bag morcellation changes total operative time (minutes) compared with uncontained power morcellation during laparoscopic myomectomy (very low certainty).
It is very uncertain whether any type of in‐bag morcellation changes morcellation operative time (minutes) compared with uncontained power morcellation during laparoscopic myomectomy (very low certainty).
It is very uncertain whether any type of in‐bag morcellation changes ease of morcellation (scale 1 to 10; 1 = very difficult, 10 = very… compared with uncontained power morcellation during laparoscopic myomectomy (very low certainty).
Misoprostol showed no clear difference in need for blood transfusion Number of participants who received blood… compared with placebo to reduce blood loss during myomectomy (low certainty).
Misoprostol showed no clear difference in duration of surgery (min) Operative time compared with placebo to reduce blood loss during myomectomy (low certainty).
Vasopressin probably leads to lower need for blood transfusion Participants who received blood transfusion compared with placebo to reduce blood loss during myomectomy (moderate certainty).
Vasopressin showed no clear difference in duration of surgery Operative time compared with placebo to reduce blood loss during myomectomy (moderate certainty).
The review found no eligible studies for this question.
Bupivicaine plus epinephrine showed no clear difference in duration of surgery (min) Operative time compared with placebo to reduce blood loss during myomectomy (low certainty).
Peri‐cervical tourniquet may leads to lower need for blood transfusion Participants who received blood transfusion compared with no treatment to reduce blood loss during myomectomy (low certainty).
It is very uncertain whether peri‐cervical tourniquet changes duration of surgery (min) Operative time compared with no treatment to reduce blood loss during myomectomy (very low certainty).
Gelatin‐thrombin matrix may leads to lower need for blood transfusion Participants who received blood transfusion compared with placebo or no treatment to reduce blood loss during myomectomy (low certainty).
Gelatin‐thrombin matrix may leads to higher duration of surgery (min) Operative time compared with placebo or no treatment to reduce blood loss during myomectomy (low certainty).
It is very uncertain whether ascorbic acid changes need for blood transfusion Participants who received blood transfusion compared with no treatment to reduce blood loss during myomectomy (very low certainty).
Ascorbic acid showed no clear difference in duration of surgery (min) Operative time compared with no treatment to reduce blood loss during myomectomy (low certainty).