Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

87 questions · 94 findings · 10 reviews

No studies found 11 · 11.7%GRADE not reported 2 · 2.1%Very low 21 · 22.3%Low 35 · 37.2%Moderate 25 · 26.6%High 0 · 0%

Motivational interviewing vs treatment

Over 50% less standard drinks per day Timeline follow back · concurrent problem alcohol and illicit drug users

Motivational interviewing (MI) showed no clear difference in greater than 50% reduction in number of standard drinks consumed per… compared with treatment (low certainty).

1 finding from 1 review

Motivational interviewing vs treatment

Abstinence from alcohol over the last 30 days · concurrent problem alcohol and illicit drug users

Motivational interviewing (MI) showed no clear difference in abstinence from alcohol over the last 30 days compared with treatment (low certainty).

1 finding from 1 review

Motivational interviewing vs treatment

Retention [ · concurrent problem alcohol and illicit drug users

Motivational interviewing (MI) showed no clear difference in retention ‐ end of treatment compared with treatment (low certainty).

2 findings from 1 review

Brief motivational interviewing (BMI) vs assessment‐only to reduce alcohol consumption

25% reduction of drinking days in the past 30 days · concurrent problem alcohol and illicit drug users

Brief motivational interviewing (BMI) showed no clear difference in 25% reduction of drinking days in the past 30 days compared with assessment‐only to reduce alcohol consumption (moderate certainty).

1 finding from 1 review

Brief motivational interviewing (BMI) vs assessment‐only to reduce alcohol consumption

50% reduction of drinking days in the past 30 days · concurrent problem alcohol and illicit drug users

Brief motivational interviewing (BMI) showed no clear difference in 50% reduction of drinking days in the past 30 days compared with assessment‐only to reduce alcohol consumption (moderate certainty).

1 finding from 1 review

Brief motivational interviewing (BMI) vs assessment‐only to reduce alcohol consumption

or more drinking days' reduction in the past 30 days · concurrent problem alcohol and illicit drug users

Brief motivational interviewing (BMI) probably leads to higher or more drinking days' reduction in the past 30 days compared with assessment‐only to reduce alcohol consumption (moderate certainty).

1 finding from 1 review

Brief motivational interviewing (BMI) vs assessment‐only to reduce alcohol consumption

Retention [ · concurrent problem alcohol and illicit drug users

Brief motivational interviewing (BMI) showed no clear difference in retention ‐ end of treatment compared with assessment‐only to reduce alcohol consumption (moderate certainty).

1 finding from 1 review

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

Cognitive behavioural therapy + motivational interviewing showed no clear difference in leaving the study early: Lost to treatment compared with standard care (low certainty).

1 finding from 1 review

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Adverse event: Death · people with both severe mental illness and substance misuse

Cognitive behavioural therapy + motivational interviewing showed no clear difference in adverse event: Death compared with standard care (low certainty).

1 finding from 1 review

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Relapse · people with both severe mental illness and substance misuse

It is very uncertain whether cognitive behavioural therapy + motivational interviewing changes relapse:* Relapse at 3 months after 9 months of treatment compared with standard care (very low certainty).

1 finding from 1 review