Misoprostol showed no clear difference in need for blood transfusion Number of participants who received blood… compared with placebo to reduce blood loss during myomectomy (low certainty).
Misoprostol showed no clear difference in duration of surgery (min) Operative time compared with placebo to reduce blood loss during myomectomy (low certainty).
It is very uncertain whether oral misoprostol one‐ to two‐hourly changes vaginal birth within 24 hours compared with oral misoprostol four‐ to six‐hourly (very low certainty).
It is very uncertain whether oral misoprostol one‐ to two‐hourly changes caesarean section compared with oral misoprostol four‐ to six‐hourly (very low certainty).
It is very uncertain whether oral misoprostol one‐ to two‐hourly changes oxytocin augmentation compared with oral misoprostol four‐ to six‐hourly (very low certainty).
It is very uncertain whether oral misoprostol one‐ to two‐hourly changes uterine hyperstimulation without fetal heart rate changes compared with oral misoprostol four‐ to six‐hourly (very low certainty).
The review found no eligible studies for this question.
Oral misoprostol may leads to lower uterine hyperstimulation with fetal heart rate changes compared with vaginal dinoprostone (low certainty).
It is very uncertain whether oral misoprostol changes oxytocin augmentation compared with vaginal dinoprostone (very low certainty).
Oral misoprostol probably leads to lower uterine hyperstimulation without fetal heart rate changes compared with vaginal dinoprostone (moderate certainty).
Oral misoprostol showed no clear difference in apgar score less than seven at five minutes compared with vaginal dinoprostone (low certainty).
Oral misoprostol showed no clear difference in admission to neonatal intensive care unit compared with vaginal dinoprostone (low certainty).
Oral misoprostol showed no clear difference in caesarean section compared with placebo/no treatment (low certainty).
Oral misoprostol showed no clear difference in vaginal birth within 24 hours compared with intravenous oxytocin (low certainty).
Oral misoprostol probably leads to lower caesarean section compared with intravenous oxytocin (moderate certainty).
It is very uncertain whether oral misoprostol changes uterine hyperstimulation with fetal heart rate changes compared with intravenous oxytocin (very low certainty).
Oral misoprostol may leads to lower oxytocin augmentation compared with intravenous oxytocin (low certainty).