Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

83 questions · 83 findings · 8 reviews · Pregnancy and Childbirth

No studies found 12 · 14.5%GRADE not reported 6 · 7.2%Very low 24 · 28.9%Low 31 · 37.3%Moderate 10 · 12%High 0 · 0%

Warm compresses vs control (hands off or no warm compress)

Intact perineum · pregnant women expecting a vaginal birth, singleton vertex presentation at term, with no medical complications

Warm compresses showed no clear difference in intact perineum compared with control (hands off or no warm compress) (moderate certainty).

1 finding from 1 review

Warm compresses vs control (hands off or no warm compress)

Perineal trauma requiring suturing · pregnant women expecting a vaginal birth, singleton vertex presentation at term, with no medical complications

It is very uncertain whether warm compresses changes perineal trauma requiring suturing compared with control (hands off or no warm compress) (very low certainty).

1 finding from 1 review

Warm compresses vs control (hands off or no warm compress)

1st degree tear · pregnant women expecting a vaginal birth, singleton vertex presentation at term, with no medical complications

It is very uncertain whether warm compresses changes 1st degree tear compared with control (hands off or no warm compress) (very low certainty).

1 finding from 1 review

Vaginal misoprostol vs placebo

Opiate use (as a proxy measure for pain) for all participants on ITT (including those without confirmed AMI) · early fetal death (less than 24 weeks)

It is very uncertain whether vaginal misoprostol changes pain (opiate use) compared with placebo (very low certainty).

1 finding from 1 review