Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

96 questions · 96 findings · 15 reviews · Headline outcomes only

No studies found 18 · 18.8%GRADE not reported 1 · 1%Very low 31 · 32.3%Low 38 · 39.6%Moderate 8 · 8.3%High 0 · 0%

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Intraventricular haemorrhage, Papile grade 3/4 · preterm infants with or at risk of respiratory distress syndrome
1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Mortality before hospital discharge · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) showed no clear difference in death (all causes) during the first hospitalisation Anytime to… compared with surfactant administration via endotracheal tube (ETT) with the… (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Neurosensory disability in survivors · preterm infants with or at risk of respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration through an endotracheal tube (S‐ETT)

Death or bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration through an endotracheal tube (S‐ETT)

Need for mechanical ventilation · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) may leads to lower mechanical ventilation at any time Any time to discharge compared with surfactant administration via endotracheal tube (ETT) with… (low certainty).

1 finding from 1 review

Intervention not reported

Co‐operation during induction ‐ Mask introduction/exposure (Mask) ICC (number of children compliant) · children

It is very uncertain whether the intervention changes co‐operation during induction ‐ Mask introduction/exposure (Mask)… (very low certainty).

1 finding from 1 review

ProSeal vs Classic laryngeal mask airway (LMA)

Inadequate oxygenation (SaO₂ < 90% on peripheral oxygen saturation) · adult patients (18 years of age and older) for positive pressure ventilation undergoing elective surgery

It is very uncertain whether proSeal changes inadequate oxygenation (SaO₂ < 90% on peripheral oxygen saturation) compared with classic laryngeal mask airway (LMA) (very low certainty).

1 finding from 1 review

ProSeal vs Classic laryngeal mask airway (LMA)

Sore throat · adult patients (18 years of age and older) for positive pressure ventilation undergoing elective surgery

ProSeal showed no clear difference in sore throat compared with classic laryngeal mask airway (LMA) (low certainty).

1 finding from 1 review

ProSeal vs Classic laryngeal mask airway (LMA)

Regurgitation · adult patients (18 years of age and older) for positive pressure ventilation undergoing elective surgery

ProSeal showed no clear difference in regurgitation compared with classic laryngeal mask airway (LMA) (low certainty).

1 finding from 1 review