Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

71 questions · 71 findings · 14 reviews · Heart

No studies found 8 · 11.3%GRADE not reported 1 · 1.4%Very low 20 · 28.2%Low 19 · 26.8%Moderate 15 · 21.1%High 8 · 11.3%

Exercise vs no exercise at longest available follow‐up

ICD, appropriate shock ( · adult patients with an implantable cardioverter defibrillator

It is very uncertain whether exercise changes ICD, appropriate shock ( compared with no exercise at longest available follow‐up (very low certainty).

1 finding from 1 review

Exercise vs no exercise at longest available follow‐up

ICD, all shocks ( · adult patients with an implantable cardioverter defibrillator

It is very uncertain whether exercise changes ICD, all shocks ( compared with no exercise at longest available follow‐up (very low certainty).

1 finding from 1 review

Exercise vs no exercise at longest available follow‐up

All‐cause mortality ( · adult patients with an implantable cardioverter defibrillator

It is very uncertain whether exercise changes all‐cause mortality ( compared with no exercise at longest available follow‐up (very low certainty).

1 finding from 1 review

Exercise vs no exercise at longest available follow‐up

Serious adverse events ( · adult patients with an implantable cardioverter defibrillator

It is very uncertain whether exercise changes serious adverse events ( compared with no exercise at longest available follow‐up (very low certainty).

1 finding from 1 review

Self‐monitoring or self‐management of oral anticoagulation vs usual care

Thromboembolic events · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

Self‐monitoring or self‐management of oral anticoagulation probably leads to lower thromboembolic events compared with standard care (moderate certainty).

1 finding from 1 review