Intervention not reported
Serious adverse events during the trial period · all trials contributing results to the summary of findings table included people with mild disease (WHO scale 1 to 3)§
The intervention showed no clear difference in serious adverse events during the trial period (low certainty).
1 finding from 1 review
Intervention not reported
Any adverse events during the trial period · all trials contributing results to the summary of findings table included people with mild disease (WHO scale 1 to 3)§
The intervention showed no clear difference in any adverse events during the trial period (low certainty).
1 finding from 1 review
Intervention not reported
Viral clearance at day 7 · all trials contributing results to the summary of findings table included people with mild disease (WHO scale 1 to 3)§
The intervention showed no clear difference in viral clearance at day 7 (low certainty).
1 finding from 1 review
Intervention not reported
Worsening of clinical status: participants with new need for invasive mechanical ventilation or death at day 28 · people with moderate to severe disease (WHO scale 4–9); all trials contributing results to the summary of findings table investigated…
It is very uncertain whether the intervention changes worsening of clinical status: participants with new need for… (very low certainty).
1 finding from 1 review
Intervention not reported
Improvement of clinical status: participants discharged alive at day 28 · people with moderate to severe disease (WHO scale 4–9); all trials contributing results to the summary of findings table investigated…
The intervention showed no clear difference in improvement of clinical status: participants discharged alive at day… (low certainty).
1 finding from 1 review
Intervention not reported
QoL at longest · people with moderate to severe disease (WHO scale 4–9); all trials contributing results to the summary of findings table investigated…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Serious adverse events during the trial period · people with moderate to severe disease (WHO scale 4–9); all trials contributing results to the summary of findings table investigated…
It is very uncertain whether the intervention changes serious adverse events during the trial period (very low certainty).
1 finding from 1 review
Intervention not reported
Any adverse events during the trial period · people with moderate to severe disease (WHO scale 4–9); all trials contributing results to the summary of findings table investigated…
The intervention showed no clear difference in any adverse events during the trial period (low certainty).
1 finding from 1 review
Intervention not reported
Viral clearance at day 7 · people with moderate to severe disease (WHO scale 4–9); all trials contributing results to the summary of findings table investigated…
The intervention showed no clear difference in viral clearance at day 7 (low certainty).
1 finding from 1 review
Intervention not reported
All‐cause mortality at day 28 · all trials contributing results to the summary of findings table included people with mild disease (WHO scale 1 to 3)§
The intervention showed no clear difference in all‐cause mortality at day 28 (moderate certainty).
1 finding from 1 review
Intervention not reported
Worsening of clinical status: admission to hospital or death within 28 days · all trials contributing results to the summary of findings table included people with mild disease (WHO scale 1 to 3)§
The intervention showed no clear difference in worsening of clinical status: admission to hospital or death within… (low certainty).
1 finding from 1 review
Intervention not reported
Cure overall negative parasitological test · patients with treating strongyloides infection
The intervention probably leads to higher cure overall negative parasitological test (moderate certainty).
1 finding from 1 review
Intervention not reported
Adverse events report of adverse events · patients with treating strongyloides infection
The intervention showed no clear difference in adverse events report of adverse events (low certainty).
1 finding from 1 review
Intervention not reported
Cure overall negative parasitological test · patients with treating strongyloides infection
The intervention showed no clear difference in cure overall negative parasitological test (low certainty).
1 finding from 1 review
Intervention not reported
Adverse events report of adverse events · patients with treating strongyloides infection
The intervention probably leads to lower adverse events report of adverse events (moderate certainty).
1 finding from 1 review
Intervention not reported
Improvement in visual impairment at 6 months · people residing in communities endemic for onchocerciasis
It is very uncertain whether the intervention changes improvement in visual impairment at 6 months (very low certainty).
1 finding from 1 review
Intervention not reported
Parasitological outcomes · people residing in communities endemic for onchocerciasis
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Clinical outcomes: improvement in optic atrophy, chorioretinitis, or sclerosing keratitis at 6 months · people residing in communities endemic for onchocerciasis
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Clinical outcomes: improvement in iridocyclitis at 6 months · people residing in communities endemic for onchocerciasis
It is very uncertain whether the intervention changes clinical outcomes: improvement in iridocyclitis at 6 months (very low certainty).
1 finding from 1 review
Intervention not reported
Clinical outcomes: improvement in punctate keratitis at 6 months · people residing in communities endemic for onchocerciasis
It is very uncertain whether the intervention changes clinical outcomes: improvement in punctate keratitis at 6 months (very low certainty).
1 finding from 1 review