Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

151 questions · 182 findings · 35 reviews · Tobacco Addiction

No studies found 8 · 4.4%GRADE not reported 1 · 0.5%Very low 53 · 29.1%Low 67 · 36.8%Moderate 39 · 21.4%High 14 · 7.7%

Intervention not reported

Nicotine tapering · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention showed no clear difference in nicotine tapering (low certainty).

1 finding from 1 review

Intervention not reported

Nicotine patch · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention showed no clear difference in nicotine patch (low certainty).

1 finding from 1 review

Intervention not reported

Fast‐acting NRT (nicotine other) · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention showed no clear difference in fast‐acting NRT (nicotine other) (low certainty).

1 finding from 1 review

Intervention not reported

Bupropion · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention showed no clear difference in bupropion (moderate certainty).

1 finding from 1 review

Intervention not reported

Fast‐acting NRT (nicotine other) · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention leads to higher fast‐acting NRT (nicotine other) (high certainty).

1 finding from 1 review

Intervention not reported

Non‐nicotine/placebo EC · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention showed no clear difference in non‐nicotine/placebo EC (low certainty).

1 finding from 1 review

Intervention not reported

Nortriptyline · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention probably leads to higher nortriptyline (moderate certainty).

1 finding from 1 review

Smoking cessation advice vs no smoking cessation counselling, grouped by intensity of intervention

Quit at longest · individuals who smoke cigarettes and are admitted to a hospital for medical or surgical care

It is very uncertain whether smoking cessation counselling changes quit at longest compared with no smoking cessation counselling, grouped by intensity of intervention (very low certainty).

4 findings from 1 review
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