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Evidence found and GRADE certainty

74 questions · 75 findings · 4 reviews · Other oral health

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No studies found 6 · 8%GRADE not reported 67 · 89.3%Very low 1 · 1.3%Low 0 · 0%Moderate 1 · 1.3%High 0 · 0%

Cyclosporin A in orabase (topical) vs Placebo (orabase)

Oral ulcers (number, size, healing time) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
  • Interventions for managing oral ulcers in Behçet's disease 2014 · Cochrane All outcomes
    Ergun 1997 (cyclosporin A in orabase vs placebo orabase, 24 patients; high risk of reporting bias): no data were presented; authors reported no clinical improvement in the number, size, and healing time of ulcers for…
    1 study · 24 participants
    GRADE not reported

Depot corticosteroids (systemic; 40 mg methylprednisolone IM every 3 weeks for 27 weeks) vs placebo injection

Mean number of oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care

Depot corticosteroids (systemic; 40 mg methylprednisolone IM every 3… showed no clear difference in mean number of oral ulcers compared with placebo (saline IM injection); GRADE not reported.

1 finding from 1 review

Interferon-alpha (systemic) vs Placebo (subcutaneous)

Safety of the intervention (adverse effects) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
  • Interventions for managing oral ulcers in Behçet's disease 2014 · Cochrane All outcomes
    Alpsoy 2002: high rate of adverse events including alopecia, leukopenia, and diarrhoea; 18 of 23 patients in the treatment arm experienced mild flu-like symptoms.
    1 study · 50 participants
    GRADE not reported

Cyclosporin (systemic; 10 mg/kg/day for 16 weeks) vs Colchicine (systemic; 1 mg daily)

Alleviation of oral aphthous ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care

Cyclosporin (systemic; 10 mg/kg/day for 16 weeks) led to higher alleviation of oral aphthous ulcers compared with colchicine (systemic; 1 mg daily); GRADE not reported.

1 finding from 1 review

Sucralfate suspension (topical) vs Placebo suspension

Episode frequency associated with oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care

Sucralfate suspension (topical) showed no clear difference in frequency of oral ulcers compared with placebo suspension; GRADE not reported.

1 finding from 1 review

Individually designed, patient-centred preventive programme: dietary counselling (snacking timing, regular meals, fermentable carbohydrates) plus toothbrushing counselling, delivered by trained dental hygienists (a multi-intervention) vs Basic prevention offered as standard in public dental clinics

Nibbling less than daily · Children aged 11 to 12 years with at least one active initial caries lesion, screened in a town in Finland
1 finding from 1 review

A 10-minute film followed by the same 30-minute one-to-one hygienist instruction on sugar consumption and dental health, plus oral hygiene, fluoride and regular visits (a multi-intervention) vs No special instructions (control)

Mean sugar consumption (self-reported, 1 to 5 scale; higher score = more positive behaviour) · Adults newly registered at a group dental practice in a suburban Dutch village, the Netherlands
1 finding from 1 review

Dietary counselling tailored to a Stage of Change (Transtheoretical Model) to increase fruit and vegetable intake (two counselling sessions) vs usual care

Vegetable consumption behaviour: proportion in the Action Stage of Change (versus Pre-Action) · Edentulous patients aged 45 to 80 years attending dental-student teaching clinics for replacement dentures, Newcastle Dental Hospital, UK
1 finding from 1 review

Dietary counselling tailored to a Stage of Change (Transtheoretical Model) to increase fruit and vegetable intake (two counselling sessions) vs usual care

Fruit consumption · Edentulous patients aged 45 to 80 years attending dental-student teaching clinics for replacement dentures, Newcastle Dental Hospital, UK
1 finding from 1 review

Individually designed, patient-centred preventive programme: dietary counselling (snacking timing, regular meals, fermentable carbohydrates) plus toothbrushing counselling, delivered by trained dental hygienists (a multi-intervention) vs Basic prevention offered as standard in public dental clinics

Eating candy less than daily · Children aged 11 to 12 years with at least one active initial caries lesion, screened in a town in Finland
1 finding from 1 review

Brief motivational interviewing (BMI) vs usual treatment alone

Alcohol consumption: consuming more than 21 units of alcohol per week · Male patients aged 16 to 35 years attending an oral and maxillofacial surgery outpatient clinic for follow-up of an alcohol-related facial…

Brief one-session, manual-guided discussion based on the principles… led to lower alcohol consumption: consuming more than 21 units of alcohol per week compared with treatment at the outpatient clinic as usual; GRADE not reported.

1 finding from 1 review

Dietary counselling tailored to a Stage of Change (Transtheoretical Model) to increase fruit and vegetable intake (two counselling sessions) vs usual care

Body‐mass index (BMI) · Edentulous patients aged 45 to 80 years attending dental-student teaching clinics for replacement dentures, Newcastle Dental Hospital, UK
1 finding from 1 review

Individually designed, patient-centred preventive programme: dietary counselling (snacking timing, regular meals, fermentable carbohydrates) plus toothbrushing counselling, delivered by trained dental hygienists (a multi-intervention) vs Basic prevention offered as standard in public dental clinics

Drinking soft drinks less than daily · Children aged 11 to 12 years with at least one active initial caries lesion, screened in a town in Finland
1 finding from 1 review

Dietary counselling tailored to a Stage of Change (Transtheoretical Model) to increase fruit and vegetable intake (two counselling sessions) vs usual care

Vegetable consumption (grams per day) · Edentulous patients aged 45 to 80 years attending dental-student teaching clinics for replacement dentures, Newcastle Dental Hospital, UK
1 finding from 1 review

Individually designed, patient-centred preventive programme: dietary counselling (snacking timing, regular meals, fermentable carbohydrates) plus toothbrushing counselling, delivered by trained dental hygienists (a multi-intervention) vs Basic prevention offered as standard in public dental clinics

Caries increment on tooth surfaces (dmfs/DMFS) (prevented fraction) · Children aged 11 to 12 years with at least one active initial caries lesion, screened in a town in Finland
2 findings from 1 review

Individually designed, patient-centred preventive programme: dietary counselling (snacking timing, regular meals, fermentable carbohydrates) plus toothbrushing counselling, delivered by trained dental hygienists (a multi-intervention) vs Basic prevention offered as standard in public dental clinics

Eating healthy snacks at least twice per day · Children aged 11 to 12 years with at least one active initial caries lesion, screened in a town in Finland
1 finding from 1 review

One-to-one dietary intervention aimed at preventing tooth erosion (e.g., reducing consumption of acidic/carbonated drinks) vs No dietary advice, or different dietary advice

Dental erosion / tooth wear (tooth wear indices) · Participants of any age receiving one-to-one dietary advice in a dental setting

The review found no eligible studies for this question.

1 finding from 1 review

One-to-one advice on sugar restriction: detailed information on the sugar content of foods, with instruction to refrain from sugar-containing foods between meals and to reduce sugar in main meals (6-week sugar restriction) vs No advice on sugar restriction

Sugar intake frequency between meals (mean number of intakes per day) · Adults with frequent sugar intake harbouring Streptococcus mutans and Streptococcus sobrinus in saliva (14 dental technical students and 6…
1 finding from 1 review

Individually designed, patient-centred preventive programme: dietary counselling (snacking timing, regular meals, fermentable carbohydrates) plus toothbrushing counselling, delivered by trained dental hygienists (a multi-intervention) vs Basic prevention offered as standard in public dental clinics

Eating warm meals more than twice per day · Children aged 11 to 12 years with at least one active initial caries lesion, screened in a town in Finland
1 finding from 1 review

Dietary counselling tailored to a Stage of Change (Transtheoretical Model) to increase fruit and vegetable intake (two counselling sessions) vs usual care

Fruit juice consumption: risk of starting to drink fruit juice · Edentulous patients aged 45 to 80 years attending dental-student teaching clinics for replacement dentures, Newcastle Dental Hospital, UK

Dietary counselling tailored to a Stage of Change (Transtheoretical… showed no clear difference in fruit juice consumption: risk of starting to drink fruit juice compared with usual care; GRADE not reported.

1 finding from 1 review