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Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

199 questions · 199 findings · 17 reviews · Metabolic and Endocrine Disorders

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No studies found 90 · 45.2%GRADE not reported 5 · 2.5%Very low 43 · 21.6%Low 37 · 18.6%Moderate 22 · 11.1%High 2 · 1%

Intervention not reported

Adverse events 1. All adverse events 2. Drop‐outs due to adverse events Interventions vs thiazolidinediones [1. 6 months to 12 months] [2. 24 weeks to 52 weeks] · participants with type 2 diabetes mellitus

The intervention may leads to lower adverse events 1. All adverse events 2. Drop‐outs due to adverse… (low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Adverse events · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes adverse events compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Surgery for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes surgery for recurrent or persistent disease compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review