Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

83 questions · 89 findings · 10 reviews

No studies found 31 · 34.8%GRADE not reported 3 · 3.4%Very low 12 · 13.5%Low 19 · 21.3%Moderate 19 · 21.3%High 5 · 5.6%

IVIg vs different infusion regimens of IVIG

Incidence of any adverse effects after treatment initiation ( · people undergoing initial treatment for KD

Primary treatment with intravenous immunoglobulin (IVIG) showed no clear difference in incidence of any adverse effects after treatment initiation ( compared with different infusion regimens of IVIG (low certainty).

1 finding from 1 review

IVIg vs prednisolone

Incidence of CAAs (acute phase) · people undergoing initial treatment for KD

It is very uncertain whether primary treatment with intravenous immunoglobulin (IVIG) changes incidence of CAAs (acute phase) compared with prednisolone (very low certainty).

1 finding from 1 review

IVIg vs prednisolone

Incidence of any adverse effects after treatment initiation ( · people undergoing initial treatment for KD

Primary treatment with intravenous immunoglobulin (IVIG) showed no clear difference in incidence of any adverse effects after treatment initiation (up to 3… compared with prednisolone (low certainty).

1 finding from 1 review

IVIg vs acetylsalicylic acid (ASA)

Incidence of any adverse effects after treatment initiation ( · people undergoing initial treatment for KD

It is very uncertain whether primary treatment with intravenous immunoglobulin (IVIG) changes incidence of any adverse effects after treatment initiation (from 30… compared with acetylsalicylic acid (ASA) (very low certainty).

1 finding from 1 review