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What do systematic reviews say?

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Evidence found and GRADE certainty

219 questions · 223 findings · 25 reviews · Eyes and Vision

No studies found 76 · 34.1%GRADE not reported 5 · 2.2%Very low 39 · 17.5%Low 75 · 33.6%Moderate 25 · 11.2%High 3 · 1.3%

Intravitreal triamcinolone acetonide injection 4 mg vs macular laser

Change in visual acuity (logMAR) ‐ 12 months (negative is better) · macular edema in diabetes

It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes change in visual acuity (logMAR) ‐ 12 months (negative is better) compared with macular laser (very low certainty).

1 finding from 1 review

Intravitreal triamcinolone acetonide injection 4 mg vs antiVEGF

Central retinal thickness μm (CRT) change at 1 year The aim of treatment is to reduce central retinal thickness so thinner is better. · macular edema in diabetes

It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes change in central retinal thickness (micron) ‐ 12 months (negative… compared with antiVEGF (very low certainty).

1 finding from 1 review