Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

974 questions · 987 findings · 137 reviews

No studies found 182 · 18.4%GRADE not reported 90 · 9.1%Very low 165 · 16.7%Low 312 · 31.6%Moderate 163 · 16.5%High 75 · 7.6%

Dexamethasone vs betamethasone – child outcomes

Any known death after randomisation (fetal, neonatal, child, child as adult) · women at risk of preterm birth

Dexamethasone showed no clear difference in any known death after randomisation (fetal, neonatal, child, child… compared with betamethasone – fetal/neonatal outcomes (moderate certainty).

1 finding from 1 review

Summary of findings for selective ß2‐adrenergic agonist vs no tocolytic agent, whilst awaiting emergency delivery

Fetal or neonatal mortality · women with fetal distress for whom the decision had been made to delivery by emergency caesarean section

Summary of findings for selective ß2‐adrenergic agonist showed no clear difference in fetal or neonatal mortality compared with no tocolytic agent, whilst awaiting emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Fetal or neonatal mortality · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

Summary of findings for IV hexoprenaline showed no clear difference in fetal or neonatal mortality compared with no tocolytic agent, whilst awaiting emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for subcutaneous terbutaline vs IV magnesium sulphate

Resolution of fetal distress on FHR tracing · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

It is very uncertain whether summary of findings for subcutaneous terbutaline changes resolution of fetal distress on FHR tracing compared with IV magnesium sulphate (very low certainty).

1 finding from 1 review

Summary of findings for subcutaneous terbutaline with continuation of oxytocic infusion vs cessation of oxytocic infusion without tocolytic agent

Fetal or neonatal mortality · women who developed uterine hyperstimulation in labour with oxytocin augmentation, but without signs of fetal distress

The review found no eligible studies for this question.

1 finding from 1 review

Routine/revealed vs selective/concealed ultrasound

Detection of fetal abnormality before 24 weeks' gestation · Fetal ultrasound assessment before 24 weeks' gestation

Routine/revealed probably leads to higher detection of fetal abnormality before 24 weeks' gestation compared with selective/concealed ultrasound (moderate certainty).

1 finding from 1 review