HALOPERIDOL + PROMETHAZINE showed no clear difference in global state: Needing restraints or seclusion by 12 hours compared with ANTIPSYCHOTIC ‐ OLANZAPINE (low certainty).
HALOPERIDOL probably leads to higher tranquillisation or asleep compared with COMBINATIONS: d. HALOPERIDOL + PROMETHAZINE (moderate certainty).
It is very uncertain whether HALOPERIDOL changes repeated need for tranquillisation compared with COMBINATIONS: d. HALOPERIDOL + PROMETHAZINE (very low certainty).
HALOPERIDOL showed no clear difference in specific behaviours ‐ aggression compared with COMBINATIONS: d. HALOPERIDOL + PROMETHAZINE (moderate certainty).
HALOPERIDOL showed no clear difference in global outcomes compared with COMBINATIONS: d. HALOPERIDOL + PROMETHAZINE (moderate certainty).
HALOPERIDOL may leads to higher adverse effects: specific ‐ acute dystonia compared with COMBINATIONS: d. HALOPERIDOL + PROMETHAZINE (low certainty).
HALOPERIDOL showed no clear difference in adverse effects: specific ‐ seizure compared with COMBINATIONS: d. HALOPERIDOL + PROMETHAZINE (low certainty).
The review found no eligible studies for this question.
Benzodiazepines may leads to lower tranquillisation or asleep: sedation ‐ medium term ‐ lorazepam vs… compared with antihistamines plus antipsychotics (low certainty).
Benzodiazepines may leads to higher tranquillisation or asleep: sedation ‐ medium term ‐ midazolam vs… compared with antihistamines plus antipsychotics (low certainty).