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Evidence found and GRADE certainty

62 questions · 66 findings · 5 reviews

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No studies found 11 · 16.7%GRADE not reported 23 · 34.8%Very low 8 · 12.1%Low 12 · 18.2%Moderate 11 · 16.7%High 1 · 1.5%

Summary of findings table ‐ Progestogens vs GnRH antagonists

Live birth or ongoing pregnancy ‐ Poor‐responders (MPA 10 mg versus GnRH antagonists) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles

Summary of findings table ‐ Progestogens showed no clear difference in live birth or ongoing pregnancy ‐ Poor‐responders (MPA 10 mg versus… compared with gnRH antagonists; GRADE not reported.

1 finding from 1 review

GnRH antagonist vs long‐course GnRH agonist

Cycle cancellation due to poor ovarian response · women undergoing assisted reproductive technology (ART)

GnRH antagonist probably leads to higher cycle cancellation due to poor ovarian response compared with long‐course GnRH agonist (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH antagonists

Oocyte pick‐up cancellation sensitivity analysis ‐ total · assisted reproduction technology cycles

Summary of findings table ‐ Progestogens showed no clear difference in oocyte pick‐up cancellation sensitivity analysis ‐ total compared with gnRH antagonists; GRADE not reported.

1 finding from 1 review

Clomiphene citrate or letrozole with or without gonadotropins (with or without midcycle antagonist) vs gonadotropins (with GnRH agonists or midcycle antagonist)

Live birth rate per woman · for controlled ovarian stimulation

Clomiphene citrate or letrozole with or without gonadotropins (with… showed no clear difference in live birth per woman compared with gonadotropins (with GnRH agonists or midcycle antagonist) (low certainty).

1 finding from 1 review

Clomiphene citrate or letrozole with or without gonadotropins (with or without midcycle antagonist) vs gonadotropins (with GnRH agonists or midcycle antagonist)

Ovarian Hyperstimulation Syndrome rate per woman ‐ not reported · for controlled ovarian stimulation

Clomiphene citrate or letrozole with or without gonadotropins (with… may leads to lower ovarian hyperstimulation syndrome per woman compared with gonadotropins (with GnRH agonists or midcycle antagonist) (low certainty).

1 finding from 1 review

Clomiphene citrate or letrozole with or without gonadotropins (with or without midcycle antagonist) vs gonadotropins (with GnRH agonists or midcycle antagonist)

Clinical pregnancy rate · for controlled ovarian stimulation

Clomiphene citrate or letrozole with or without gonadotropins (with… showed no clear difference in clinical pregnancy rate per woman compared with gonadotropins (with GnRH agonists or midcycle antagonist) (moderate certainty).

1 finding from 1 review

Clomiphene citrate or letrozole with or without gonadotropins (with or without midcycle antagonist) vs gonadotropins (with GnRH agonists or midcycle antagonist)

Cancellation rate per woman · for controlled ovarian stimulation

Clomiphene citrate or letrozole with or without gonadotropins (with… may leads to higher cancellation rate per woman compared with gonadotropins (with GnRH agonists or midcycle antagonist) (low certainty).

1 finding from 1 review