Findings

What do systematic reviews say?

45 questions · 46 findings · 9 reviews

No studies found 10 · 21.7%GRADE not reported 4 · 8.7%Very low 18 · 39.1%Low 5 · 10.9%Moderate 7 · 15.2%High 2 · 4.3%

Death prior to hospital discharge · Preterm infants

The intervention showed no clear difference in death prior to hospital discharge (high certainty).

1 finding from 1 review

Glutamine supplementation to prevent morbidity and mortality in preterm infants 2016 · Cochrane Headline outcomes only
RR 0.97 [0.8, 1.17]
12 studies · 2877 participants
High

Neurodevelopmental impairment · Preterm infants

The intervention showed no clear difference in neurodevelopmental impairment (low certainty).

1 finding from 1 review

Glutamine supplementation to prevent morbidity and mortality in preterm infants 2016 · Cochrane Headline outcomes only
RR 1.07 [0.59, 1.92]
1 study · 72 participants
Low

Invasive infection · Preterm infants

The intervention showed no clear difference in invasive infection (moderate certainty).

1 finding from 1 review

Glutamine supplementation to prevent morbidity and mortality in preterm infants 2016 · Cochrane Headline outcomes only
RR 0.94 [0.86, 1.04]
11 studies · 2815 participants
Moderate

Necrotising enterocolitis · Preterm infants

The intervention showed no clear difference in necrotising enterocolitis (moderate certainty).

1 finding from 1 review

Glutamine supplementation to prevent morbidity and mortality in preterm infants 2016 · Cochrane Headline outcomes only
RR 0.83 [0.66, 1.06]
11 studies · 2849 participants
Moderate

Induction of remission at 4 weeks · Childen (<16 years old)with active Crohn's disease

The intervention showed no clear difference in induction of remission at 4 weeks (low certainty).

1 finding from 1 review

Glutamine for induction of remission in Crohn's disease 2016 · Cochrane Headline outcomes only
RR 0.8 [0.31, 2.04]
1 study · 18 participants
Low