Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

74 questions · 77 findings · 5 reviews

No studies found 32 · 41.6%GRADE not reported 1 · 1.3%Very low 20 · 26%Low 17 · 22.1%Moderate 7 · 9.1%High 0 · 0%

Metformin combined with clomiphene citrate vs clomiphene

Ovulation rate · women with polycystic ovary syndrome

Metformin combined with clomiphene citrate probably leads to higher ovulation rate per woman compared with clomiphene citrate alone (moderate certainty).

1 finding from 1 review · compare the 2 reviews

Metformin combined with clomiphene citrate vs clomiphene

Miscarriage · women with polycystic ovary syndrome

Metformin combined with clomiphene citrate may leads to higher miscarriage rate per woman compared with clomiphene citrate alone (low certainty).

1 finding from 1 review · compare the 2 reviews

Metformin vs clomiphene

Live birth rate per woman aParticipants with BMI < 30 kg/m2 or ≤ 32 kg/m2 · women with polycystic ovary syndrome

It is very uncertain whether metformin changes live birth rate per woman Participants with BMI < 30 kg/m2 or ≤ 32… compared with clomiphene citrate (very low certainty).

1 finding from 1 review · compare the 2 reviews

Metformin vs clomiphene

Live birth rate per woman aParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome

It is very uncertain whether metformin changes live birth rate per woman Participants with BMI ≥ 30 kg/m2a compared with clomiphene citrate (very low certainty).

1 finding from 1 review · compare the 2 reviews