Higher showed no clear difference in asthma ‐ infant incidence compared with lower PUFA intake (low certainty).
It is very uncertain whether higher changes dermatitis/eczema ‐ infant incidence compared with lower PUFA intake (very low certainty).
It is very uncertain whether higher changes allergic rhinitis ‐ infant incidence compared with lower PUFA intake (very low certainty).
It is very uncertain whether higher changes food allergy ‐ infant incidence compared with lower PUFA intake (very low certainty).
It is very uncertain whether higher changes all allergic disease ‐ childhood incidence compared with lower PUFA intake (very low certainty).
It is very uncertain whether higher changes asthma ‐ childhood incidence compared with lower PUFA intake (very low certainty).
It is very uncertain whether higher changes dermatitis/eczema ‐ childhood incidence compared with lower PUFA intake (very low certainty).
It is very uncertain whether higher changes food allergy ‐ childhood incidence compared with lower PUFA intake (very low certainty).
PUFA may leads to higher seizure freedom compared with placebo (low certainty).
PUFA showed no clear difference in 50% reduction in seizures frequency (12 weeks) ‐ Per protocol data ‐… compared with placebo (low certainty).
PUFA may leads to higher 50% reduction in seizures frequency (12 weeks) ‐ Per protocol data ‐… compared with placebo (low certainty).
PUFA showed no clear difference in 50% reduction in seizures frequency (6 weeks) compared with placebo (moderate certainty).
The review found no eligible studies for this question.
PUFA showed no clear difference in gastrointestinal effects compared with placebo (low certainty).