Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

374 questions · 393 findings · 47 reviews · Headline outcomes only

No studies found 73 · 18.6%GRADE not reported 16 · 4.1%Very low 164 · 41.7%Low 85 · 21.6%Moderate 36 · 9.2%High 19 · 4.8%

Exposure to clomiphene citrate for subfertility vs general population and endometrial cancer risk

Endometrial cancer · Women treated with ovary‐stimulating drugs for subfertility

It is very uncertain whether exposure to clomiphene citrate for subfertility changes endometrial cancer compared with general population and endometrial cancer risk (very low certainty).

1 finding from 1 review

Exposure to any ovary‐stimulating drugs for subfertility vs untreated subfertile women and endometrial cancer risk

Endometrial cancer · Women treated with ovary‐stimulating drugs for subfertility

It is very uncertain whether exposure to any ovary‐stimulating drugs for subfertility changes endometrial cancer compared with untreated subfertile women and endometrial cancer risk (very low certainty).

1 finding from 1 review

Exposure to any ovary‐stimulating drugs for subfertility vs general population and endometrial cancer risk

Endometrial cancer · Women treated with ovary‐stimulating drugs for subfertility

It is very uncertain whether exposure to any ovary‐stimulating drugs for subfertility changes endometrial cancer compared with general population and endometrial cancer risk (very low certainty).

1 finding from 1 review

Exposure to clomiphene citrate and gonadotropins for subfertility vs untreated subfertile women and endometrial cancer risk

Endometrial cancer · Women treated with ovary‐stimulating drugs for subfertility

It is very uncertain whether exposure to clomiphene citrate and gonadotropins for subfertility changes endometrial cancer compared with untreated subfertile women and endometrial cancer risk (very low certainty).

1 finding from 1 review

Exposure to clomiphene citrate and gonadotropins for subfertility vs general population and endometrial cancer risk

Endometrial cancer · Women treated with ovary‐stimulating drugs for subfertility

It is very uncertain whether exposure to clomiphene citrate and gonadotropins for subfertility changes endometrial cancer compared with general population and endometrial cancer risk (very low certainty).

1 finding from 1 review

Exposure to pulsed magnetic fields (in addition to self‐care and protective footwear) vs self‐care and footwear

Ulcer healing · ulceration and other skin changes caused by nerve damage in leprosy
2 findings from 1 review

Decision aids for informed consent vs usual care

Congruence between informed values and choice ‐ all studies Based on the proportion of participants who made a decision that aligned with what was most important to them. Assessed soon after exposure to the decision aid. · adults considering treatment or screening decisions

Patient decision aids probably leads to higher congruence between informed values and choice ‐ all studies Based on… compared with usual care (moderate certainty).

1 finding from 1 review

Single‐incision slings vs retropubic minimally‐invasive slings

Number of women with mesh exposure, extrusion or erosion in any area · women with urinary incontinence

Single‐incision slings showed no clear difference in number of women with mesh exposure, extrusion or erosion in any area compared with retropubic minimally‐invasive slings (low certainty).

1 finding from 1 review

Single‐incision slings vs transobturator minimally‐invasive slings

Number of women with mesh exposure, extrusion or erosion in any area · women with urinary incontinence

Single‐incision slings leads to lower number of women with mesh exposure, extrusion or erosion in any area compared with transobturator minimally‐invasive slings (high certainty).

1 finding from 1 review

Single‐incision slings vs autologous fascial slings

Number of women with mesh exposure, extrusion or erosion in any area · women with urinary incontinence

Single‐incision slings showed no clear difference in number of women with mesh exposure, extrusion or erosion in any area compared with autologous fascial slings (low certainty).

1 finding from 1 review