Findings

What do systematic reviews say?

43 questions · 43 findings · 4 reviews · Pregnancy and Childbirth

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No studies found 6 · 14%GRADE not reported 2 · 4.7%Very low 24 · 55.8%Low 11 · 25.6%Moderate 0 · 0%High 0 · 0%

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

Neonatal colonization with GBS within the first seven days of life · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes neonatal colonization with GBS within the first seven days of life compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Vaginal chlorhexidine during labour to prevent early‐onset neonatal group B streptococcal infection 2014 · Cochrane Headline outcomes only
RR 0.64 [0.4, 1.01]
3 studies · 328 participants
Very low

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

Adverse (mild) effects in the mother · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes adverse (mild) effects in the mother compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Vaginal chlorhexidine during labour to prevent early‐onset neonatal group B streptococcal infection 2014 · Cochrane Headline outcomes only
RR 8.5 [1.6, 45.28]
3 studies · 1066 participants
Very low

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

Adverse (mild) effects in the neonate · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

1 finding from 1 review

Vaginal chlorhexidine during labour to prevent early‐onset neonatal group B streptococcal infection 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1066 participants
GRADE not reported