Findings

What do systematic reviews say?

46 questions · 46 findings · 4 reviews · Infectious Diseases

No studies found 4 · 8.7%GRADE not reported 19 · 41.3%Very low 9 · 19.6%Low 9 · 19.6%Moderate 5 · 10.9%High 0 · 0%

Pruritis · Non‐immune adults and children travelling to malaria‐endemic settings

Mefloquine led to lower pruritis compared with doxycycline; GRADE not reported.

1 finding from 1 review

Mefloquine for preventing malaria during travel to endemic areas 2017 · Cochrane Headline outcomes only
RR 0.52 [0.3, 0.91]
2 studies · 1794 participants
GRADE not reported

Photosensitivity · Non‐immune adults and children travelling to malaria‐endemic settings

Mefloquine led to lower photosensitivity compared with doxycycline; GRADE not reported.

1 finding from 1 review

Mefloquine for preventing malaria during travel to endemic areas 2017 · Cochrane Headline outcomes only
RR 0.08 [0.05, 0.11]
2 studies · 1875 participants
GRADE not reported

Vaginal thrush · Non‐immune adults and children travelling to malaria‐endemic settings

Mefloquine led to lower vaginal thrush compared with doxycycline; GRADE not reported.

1 finding from 1 review

Mefloquine for preventing malaria during travel to endemic areas 2017 · Cochrane Headline outcomes only
RR 0.1 [0.06, 0.16]
1 study · 1761 participants
GRADE not reported

Duration of diarrhoea · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 230 participants
Moderate

Stool volume · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 336 participants
Moderate

Bacteriological failure · Adults and children with cholera diarrhoea

Tetracycline probably leads to lower bacteriological failure compared with doxycycline (moderate certainty).

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
RR 0.2 [0.06, 0.68]
2 studies · 198 participants
Moderate