Findings

What do systematic reviews say?

52 questions · 52 findings · 6 reviews · Common Mental Disorders

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No studies found 2 · 3.8%GRADE not reported 0 · 0%Very low 14 · 26.9%Low 24 · 46.2%Moderate 10 · 19.2%High 2 · 3.8%

Lithium vs topiramate

Efficacy: response (continuous) YMRS change by ≥ 50% at end of study · acute mania

The review found no eligible studies for this question.

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lithium vs clonazepam

Efficacy: response (continuous) CGI change from baseline to end of study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 41 participants
Moderate

Lithium vs ECT

Efficacy: response (continuous) MRS mean change from baseline to end of study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Low

Lithium vs all antimanic agents

Efficacy: response (continuous) YMRS/BPRS change from baseline to end of study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
19 studies · 2410 participants
Low

Lithium vs valproate

Efficacy: response (continuous) Change in YMRS (ITT‐LOCF) from baseline to end of study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 398 participants
Very low

Antidepressants vs placebo

Improvement in depression at 6‐12 weeks: HAM‐D score (continuous) · adults living with HIV and depression

1 finding from 1 review

Antidepressants for depression in adults with HIV infection 2018 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 357 participants
Low

Selective serotonin reuptake inhibitors vs atypical agent

Improvement in depression at 6‐12 weeks: HAM‐D score (continuous) · adults living with HIV and depression

1 finding from 1 review

Antidepressants for depression in adults with HIV infection 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 70 participants
Low

Selective serotonin reuptake inhibitors vs tricyclic antidepressants (TCAs)

Improvement in depression at 6‐12 weeks: HAM‐D score (continuous) · adults living with HIV and depression

1 finding from 1 review

Antidepressants for depression in adults with HIV infection 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Cognitive behaviour therapy vs supportive psychotherapy

Short‐term improvement as measured on a continuous scale ( · adults with panic disorder

1 finding from 1 review

Psychological therapies for panic disorder with or without agoraphobia in adults: a network meta‐analysis 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 152 participants
Low

Cognitive behaviour therapy vs psychodynamic psychotherapy

Short‐term improvement as measured on a continuous scale ( · adults with panic disorder

1 finding from 1 review

Psychological therapies for panic disorder with or without agoraphobia in adults: a network meta‐analysis 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 54 participants
Very low

Intervention not reported

Short‐term improvement as measured on a continuous scale ( · adult patients with panic disorder with or without agoraphobia

1 finding from 1 review

Psychological therapies for panic disorder with or without agoraphobia in adults: a network meta‐analysis 2016 · Cochrane Headline outcomes only
no estimate extracted
57 studies · 2318 participants
Low

Cognitive behaviour therapy vs no treatment

Short‐term improvement as measured on a continuous scale ( · adults with panic disorder

1 finding from 1 review

Psychological therapies for panic disorder with or without agoraphobia in adults: a network meta‐analysis 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 27 participants
Low