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Evidence found and GRADE certainty

82 questions · 98 findings · 11 reviews

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No studies found 29 · 29.6%GRADE not reported 15 · 15.3%Very low 14 · 14.3%Low 26 · 26.5%Moderate 14 · 14.3%High 0 · 0%

Clindamycin plus aminoglycoside vs regimens containing quinolone

Clinical cure according to criteria established by study authors Mild‐moderate PID · women with PID

It is very uncertain whether regimens containing clindamycin plus aminoglycoside changes clinical cure according to criteria established by authors… compared with regimens containing quinolone (very low certainty).

1 finding from 1 review

Clindamycin plus aminoglycoside vs regimens containing quinolone

Clinical cure according to criteria established by study authors Severe PID · women with PID

Regimens containing clindamycin plus aminoglycoside showed no clear difference in clinical cure according to criteria established by authors Severe PID compared with regimens containing quinolone (low certainty).

1 finding from 1 review

Clindamycin plus aminoglycoside vs regimens containing quinolone

Adverse events: any antibiotic‐related adverse event leading to discontinuation of therapy · women with PID

It is very uncertain whether regimens containing clindamycin plus aminoglycoside changes adverse events: any antibiotic‐related adverse event leading to… compared with regimens containing quinolone (very low certainty).

1 finding from 1 review

Clindamycin plus aminoglycoside vs regimens containing cephalosporin

Clinical cure according to criteria established by study authors Mild‐moderate PID · women with PID

Regimens containing clindamycin plus aminoglycoside showed no clear difference in clinical cure according to criteria established by authors… compared with regimens containing cephalosporin (low certainty).

1 finding from 1 review

Clindamycin plus aminoglycoside vs regimens containing cephalosporin

Clinical cure according to criteria established by study authors Severe PID · women with PID

Regimens containing clindamycin plus aminoglycoside showed no clear difference in clinical cure according to criteria established by authors Severe PID compared with regimens containing cephalosporin (moderate certainty).

1 finding from 1 review

Clindamycin plus aminoglycoside vs regimens containing cephalosporin

Adverse events: any antibiotic‐related adverse event leading to discontinuation of therapy · women with PID

It is very uncertain whether regimens containing clindamycin plus aminoglycoside changes adverse events: any antibiotic‐related adverse event leading to… compared with regimens containing cephalosporin (very low certainty).

1 finding from 1 review

Single preoperative dose of systemic antibiotics (clindamycin 600 mg), total chemo-mechanical debridement and root filling vs Matched placebo, total chemo-mechanical debridement and root filling

Swelling (mean) · Adults with symptomatic apical periodontitis (no signs of spreading infection or systemic involvement)

The review found no eligible studies for this question.

3 findings from 1 review

Single preoperative dose of systemic antibiotics (clindamycin 600 mg), total chemo-mechanical debridement and root filling vs Matched placebo, total chemo-mechanical debridement and root filling

Pain at 24 hours · Adults with symptomatic apical periodontitis (no signs of spreading infection or systemic involvement)
1 finding from 1 review

Single preoperative dose of systemic antibiotics (clindamycin 600 mg), total chemo-mechanical debridement and root filling vs Matched placebo, total chemo-mechanical debridement and root filling

Pain at 48 hours · Adults with symptomatic apical periodontitis (no signs of spreading infection or systemic involvement)
1 finding from 1 review